Publications by authors named "Kudzai P E Masunda"

Objectives: This study was conducted to explore the epidemiology and microbiological pattern of the cholera outbreaks that occurred in Zimbabwe from 2018 to 2019.

Study Setting And Design: This descriptive study used secondary data of 9971 out of 10 730 suspected cases from the Zimbabwean National Diseases Surveillance system and microbiology data of 241 out of 371 patients from the National Microbiology Reference Laboratory in Harare, for the period 5 September 2018 and 3 January 2019. Descriptive analysis was performed to describe the characteristics of the outbreak in terms of person, place and time.

View Article and Find Full Text PDF

: Treatment for urinary tract infections (UTIs) is usually empiric and is based on local antimicrobial resistance data. These data, however, are scarce in low-resource settings. The aim of this study is to determine the impact of antibiotic treatment on clinical and bacteriological outcomes in patients presenting with UTI symptoms to primary care in Harare.

View Article and Find Full Text PDF

Background Overuse of antibiotics is one of the main drivers for antimicrobial resistance (AMR). Globally, most antibiotics are prescribed in the outpatient setting. This survey aimed to explore attitudes and practices with regards to microbiology tests, AMR and antibiotic prescribing among healthcare providers at public primary health clinics in Harare, Zimbabwe.

View Article and Find Full Text PDF

Antimicrobial resistance surveillance data is lacking from many resource-limited settings mainly due to limited laboratory testing. Novel culture systems may address some of the limitations of conventional culture media and expand the availability of microbiology services. The aims of this study were to evaluate the performance of InTray COLOREX Screen/ESBL and Compact Dry for the detection of uropathogens and of extended-spectrum beta-lactamase (ESBL)-producing organisms from urine samples.

View Article and Find Full Text PDF
Article Synopsis
  • People living with HIV are at a higher risk for infections caused by antibiotic-resistant organisms, especially in places with limited medical resources.
  • A study in Harare, Zimbabwe, examined adults with urinary tract infection (UTI) symptoms and found that HIV-infected individuals were more likely to have infections with ESBL-producing bacteria.
  • Results indicated that HIV patients had more than double the odds of being infected with these resistant bacteria, highlighting the need to consider HIV status when prescribing antibiotics for UTIs.
View Article and Find Full Text PDF

Antimicrobial resistance (AMR) is compromising our ability to successfully treat infections. There are few data on gram-negative AMR prevalence in sub-Saharan Africa especially from the outpatient setting. This study aims to investigate the prevalence of and underlying molecular mechanisms for AMR in gram-negative bacilli causing urinary tract infections (UTIs) in Zimbabwe.

View Article and Find Full Text PDF