Bragg Grating Assisted Sagnac Interferometer in SiO-AlO-LaO Polarization-Maintaining Fiber for Strain-Temperature Discrimination.

Polarization-maintaining fibers (PMFs) have always received great attention in fiber optic communication systems and components which are sensitive to polarization. Moreover, they are widely applied for high-accuracy detection and sensing devices, such as fiber gyroscope, electric/magnetic sensors, multi-parameter sensors, and so on. Here, we demonstrated the combination of a fiber Bragg grating (FBG) and Sagnac interference in the same section of a new type of PANDA-structure PMF for the simultaneous measurement of axial strain and temperature.

Modified Powder-in-Tube Technique Based on the Consolidation Processing of Powder Materials for Fabricating Specialty Optical Fibers.

The objective of this paper is to demonstrate the interest of a consolidation process associated with the powder-in-tube technique in order to fabricate a long length of specialty optical fibers. This so-called Modified Powder-in-Tube (MPIT) process is very flexible and paves the way to multimaterial optical fiber fabrications with different core and cladding glassy materials. Another feature of this technique lies in the sintering of the preform under reducing or oxidizing atmosphere.

[Spectral and fluorescent study of the interaction of squarylium dyes, derivatives of 3H-indolium, with albumins].

Noncovalent interactions of intraionic squarylium dyes, derivatives of 3H-indolium, as well as the structurally analogous ionic indodicarbocyanine dye with serum albumins (human, bovine, rat) and, for comparison, with ovalbumin has been studied by spectral and fluorescent methods. The hydrophilic squarylium dye with sulfonate groups was found to interact with albumins more efficiently, which is probably due to the double negative charge on the dye molecule at the expense of the sulfonate groups and the ability to form hydrogen bonds with albumin. The hydrophilic indodicarbocyanine dye without the squarylium group in its structure binds to albumins much more weaker than the structurally analogous squarylium dye.

Sensory hybrid host materials for the selective chromo-fluorogenic detection of biogenic amines.

Pyrylium-containing mesoporous materials have been used for the chromo-fluorogenic sensing of biogenic amines in an aqueous environment.

[Clinical effect of radiotherapy in the treatment of non-Hodgkin's lymphoma in children].

The results of combined treatment were analysed retrospectively in 85 children with nonlymphoblastic non-Hodgkin's lymphomas (NHL) of I-II-III stages (Ann Arbor). The importance of involved-field radiation therapy (IFRT) combined with ACOP, MEV, COP chemotherapy was assessed. All patients experienced high grade nonlymphoblastic subtypes of NHL as follows: follicular center cells, undifferentiated, immunoblastic (Lukes-Collins classification).

[Malignant non-Hodgkin lymphoma in children: factors of prognosis and results of therapy].

The analysis included 187 cases of infantile non-Hodgkin's disease. It has identified Ann Arbor System stage and histological pattern of tumor (Lukes-Collins and Kiel) as a reliable and significant factor of prognosis.

[A multifactorial analysis of the combined action of an antibiotic and a low-molecular immunomodulator of microbial origin in experimental plague infection].

The combined effect of doxycycline and a low molecular weight immunomodulator of microbial origin was studied in experimental plague infection with mathematical design of the experiment. Synergism of the action of the antibiotic and immunomodulator used in subtherapeutic doses was observed. The action was the most pronounced when the drugs were applied therapeutically.

[Isolation and identification of an antibiotic from culture 8-86].

An antibiotic complex was isolated from culture 8-86 referred to Bacillus. The complex consisted of components 8-86A and 8-86B active against gram-negative organisms. By its physico-chemical properties such as IR and UV spectra, amino acid composition, specific rotation and fatty acid composition component 8-86B was shown to be close to polymyxin F.

[Multifactorial experiment on the combined action of doxycycline and a low molecular weight immunomodulator of microbial origin in experimental anthrax infection].

Chemotherapeutic efficacy of combined therapy of experimental anthrax infection with subtherapeutic doses of doxycycline and a low molecular weight immunomodulator of microbial origin was studied with mathematical design of the experiment and multifactorial analysis. A marked synergistic effect of oral doxycycline and the immunomodulator was observed. The results of the multifactorial experiment were computer processed and polynomial statistic models (the second order equations) describing the survival rate and mean lifespan (MLS) were derived.

[Multifactor analysis of the combined use of an antibiotic and a low molecular weight immunomodulator of microbial origin in experimental plague infection].

Multifactorial analysis of the combined effect of rifampicin and a low molecular immunomodulator of microbial origin in experimental plague infection was performed. Synergism of the antibiotic used in the subtherapeutic doses and the immunomodulator was shown. By the results of the study polynomial statistic models of the second order describing the survival rate and average life-span of the experimental animals were developed and nomographs (equal level curves) were plotted for rapid estimating the therapy quantitative parameters.

[Vascular mechanisms of disorders of rheological properties of the blood in patients with myocardial infarction].

The contribution made by vascular factors to impairment of blood rheological properties was demonstrated on the basis of examination of 65 apparently healthy persons by using a vascular occlusion test. The vascular endothelium showed a decrease in fibrinolytic, anticoagulant, antiaggregatory activities. The new term "hemorheological tolerance to vascular occlusion" was proposed to use.

[Combined chemotherapy of experimental infection in neutropenia].

A significant decrease in resistance to infections caused by gramnegative pathogens was observed in mice with neutropenia induced by cytostatics. Efficacy of schemes for combined chemotherapy with beta-lactams, aminoglycosides and a novel peptide antibiotic was studied on model infections in mice with neutropenia. In the neutropenic mice with sepsis caused by Pseudomonas the peptide antibiotic administered parenterally in a single dose of 50 micrograms/kg provided high therapeutic activity.

[Study of patulin by NMR and mass spectroscopy].

Patulin was studied by NMR and mass spectrometry. On the basis of the 1H and 13C NMR spectral analysis and experiments on double homo-(1H NMR) and heteronuclear (13C NMR) resonances complete assigning of the proton and carbon signals was achieved. Patulin was studied mass spectrometrically with using high performance mass spectrometry and the DADI technique.

[Structure of galtamycin].

Structure of galtamycin, a novel anthracycline antibiotic was assessed with 1H NMR, 13C NMR and mass spectroscopy. Galtamycin includes an unusual aglycone i.e.

[Kafamycin--a new pyrrol ether antibiotic].

Cafamycin is a novel polyether antibiotic active against gram-positive bacteria. It was isolated from the culture fluid of Streptomyces sp., an organism producing the anthracycline antibiotic galtamycin.

[Isolation and identification of an antileukemia substance from Coprinus radiatus].

Conditions for cultivation of basidiomycete Coprinus radiatus on agar media and its submersion fermentation were developed. An antibiotic was isolated from the fermentation broth filtrate by extraction with ethyl acetate followed by purification on a column with silica gel. The antibiotic had a pronounced in vivo effect on hemoblastosis La.

[Mass spectrophotometric study of the antibiotic granaticin].

A culture of Streptomyces sp. producing a substance with antibacterial and antitumor activity was isolated from a soil sample collected in the Gorno-Altai Autonomous Province. By its UV, NMR and mass spectra the antibiotic was identified as granaticin.

[The antibiotic galtamycin. Its fermentation, isolation, physicochemical and biological properties].

A culture of Streptomyces sp., producing an antibiotic named galtamycin was isolated from a soil sample collected in the Gorno-Altai Autonomous Region. The antibiotic belongs to anthracyclines.

[The antibiotic galtamycin. The structure of galtamycinone].

The structure of galtamycinone, a chromophore moiety of galtamycin, a new antitumor antibiotic was determined by spectral analysis, i.e. UV, NMR and mass spectrometry.

[Spatial perception and vestibulomotor reactions in man].

Postural responses to transcutaneous galvanic stimulation of the right labyrinth were recorded by means of a stabilograph in normal human subjects in various head positions as well as under the illusion of head and trunk rotation induced by vibration of the gluteus maximum muscle. The direction of the vestibulo-motor response was determined by the position of the head: in a normal head position the body swayed in the frontal plane, whereas with the head turned 90 degrees it moved in the sagittal plane. During the illusory head and trunk 90 degrees rotation the responses were sagittally directed like those recorded in the real head-turned-sideways position.

[Structure of the antibiotic virenomycin].

To identify the structure of virenomycin, a new antitumor antibiotic consisting of components V and M, its acetyl and permethyl derivatives, as well as products of acid methanolysis and their derivatives were obtained. The IR-, NMR- and mass-spectra of the above compounds are presented. Based on an analysis of the spectral data the structure of virenomycin is suggested.

[Separation and characteristics of the components of the antibiotic virenomycin].

The composition of virenomycin, a new antitumor antibiotic was studied. Two components V and M were detected with high resolution liquid chromatography and thin layer chromatography on siluphol (Czechoslovakia) and silica gel (Merk, BRD). A preparative method for separation of the antibiotic components with the use of chromatography on columns with silica gel was developed.