Publications by authors named "Kucy Pon"

Article Synopsis
  • Liquid silicone is an affordable injectable option for soft tissue enhancement, but it carries a risk of delayed granuloma formation linked to high levels of tumor necrosis factor-α.
  • A case was reported involving persistent silicone granulomas after facial injections, which were successfully treated using tumor necrosis factor-α blockade.
  • Both this case and prior studies suggest that this treatment is effective for managing foreign body granulomas caused by silicone.
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Treating actinic keratosis (AK) and photodamaged skin is critical to reduce the risk of progression to skin cancer. Laser resurfacing for AK treatment is available as either lesion-directed or field therapy. Laser resurfacing removes the superficial epidermis and dermis containing actinic damage, promoting re-epithelialization of healthy skin.

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Purpose: This review aimed to assess the quality and efficacy of tools currently used in breast cancer patients to score radiation dermatitis (RD), a common debilitating side effect of radiotherapy (RT).

Methods: A search was conducted through Ovid Medline, Embase, and Cochrane Central Register of Controlled Trials databases on 14 February 2020. English articles that evaluated an instrument's use in assessing RD among breast cancer patients receiving external beam RT were included.

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Purpose: Severe radiation dermatitis (RD) is distressing and may have adverse long-term effects including fibrosis and telangiectasia. Treatment interruptions due to severe RD may increase the risk of recurrence. Two randomized trials of Mepitel film demonstrated efficacy in preventing severe RD in breast cancer, but this product has not been widely adopted in North America.

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Article Synopsis
  • Botulinum neurotoxin (BoNT) injections are the most popular non-surgical cosmetic treatment and are gaining attention from practitioners worldwide.
  • The article discusses new botulinum toxins in development or nearing market approval in the USA and Canada, such as daxibotulinumtoxin A, prabotulinumtoxin A, letibotulinumtoxin A, and botulinum toxin E.
  • These new neurotoxins, while similar in effectiveness, offer unique benefits like longer-lasting results, fewer animal-derived components, and quicker effects with shorter durations.
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Radiation dermatitis is a common adverse effect of radiotherapy (RT) in breast cancer patients. Although radiation dermatitis is reported by either the clinician or the patient, previous studies have shown disagreement between clinician-reported outcomes (CROs) and patient-reported outcomes (PROs). This review evaluated the extent of discordance between CROs and PROs for radiation dermatitis.

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Despite the prevalence of radiation dermatitis in breast cancer patients, current practice guidelines for its treatment are limited. We aimed to discuss the quality of evidence for the barrier-forming Mepitel Film for prophylaxis of radiation dermatitis, and argue for further investigation into evidence-based management of skin toxicities. Two studies assessing Mepitel Film were critically evaluated.

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Background: Pulsed dye laser has been used to decrease erythema and telangiectasia associated with scars, including surgical scars. There is limited evidence indicating improved surgical scar appearance if pulsed dye laser treatments are commenced immediately at the time of suture removal.

Objective: To determine whether a single one-pass pulsed dye laser treatment at the time of suture removal can improve the appearance of surgical scars.

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Background: Cutis laxa is a heterogeneous group of inherited and acquired disorders characterized clinically by loose skin and histologically by altered elastic tissue. Heavy chain deposition disease is a very rare monoclonal immunoglobulin disorder, distinct from multiple myeloma, in which there is production and deposition of defective immunoglobulin heavy chains without light chain deposition.

Objective: We describe a case of acquired cutis laxa associated with heavy chain deposition disease.

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