Two-Dimensional Correlation Spectroscopy (2D-COS) Tracking of the Formation of Selected Transition Metal Compounds Cu(II) and Cd(II) With Cinchonine and Their Impact on Model Components of Erythrocytes.

Cinchonine is a quinoline alkaloid known for its antimalarial properties. Due to the advantages of using compounds of metal ions with alkaloids, a copper(II) compound with cinchonine was synthesized, and, for comparative purposes, a cadmium(II) compound with cinchonine. During the synthesis, the emerging interactions between the metal ion and cinchonine were studied.

Raman and resonance Raman spectroscopic study of red blood cells in patients diagnosed with malaria.

Raman spectroscopy was used to study erythrocytes collected from patients diagnosed with malaria at the University Hospital in Kraków and from healthy volunteers. A laser line with a wavelength of 442 nm was used to induce the Raman resonance of haem, while a laser with a wavelength of 785 nm was used for the normal Raman effect. The results were analysed using Principal Component Analysis.

Analysis of the Effect of Layer Height on the Interlayer Bond in Self-Compacting Concrete Mix in Slab Elements.

This paper presents a study on the influence of the layered casting technology of self-compacting concrete (SCC) on the load-bearing capacity of interlayer bond in slab elements. The research was conducted on slab elements with dimensions of 750 × 750 × 150 mm, concreted from a single point of concrete delivery. The aim of this study was to analyse the influence of the height of the concreting top layer on the bond strength between the layers.

Impact of Element Size on Rebar-Concrete Interface Microstructure Using X-ray Computed Tomography.

This paper investigates the impact of element size on the microstructure of the steel-concrete interface in self-compacting concrete (SCC). Experiments were conducted on two types of test elements: a deep beam measuring 1440 × 640 × 160 mm and a wall element measuring 2240 × 1600 × 160 mm. The SCC mix was consistently pumped from the top, using a single casting point located near the formwork's edge.

Synthesis and Study of Building Blocks with Dibenzo[]oxepine: Potential Microtubule Inhibitors.

The synthesis of biphenylmethoxydibenzo[]oxepine or photoswitchable fluorinated dibenzo[]oxepine derivatives with one or three azo bonds, potential microtubule inhibitors, is described. Our studies provide a concise method for constructing derivatives containing the dibenzo[]oxepine skeleton. An analysis of products was run using experimental and theoretical methods.

Antibiotic-Resistant Strains of Helicobacter pylori in 50 Antibiotic Treatment-Naive Children in Northeast Poland Diagnosed by Gastric or Duodenal Biopsy Between February 2019 and May 2022.

BACKGROUND In recent years, an increasing prevalence of Helicobacter pylori resistance to antibiotics has been observed. The aim of this study was to assess antibiotic resistance of Helicobacter pylori in previously untreated children from northeast Poland. MATERIAL AND METHODS Inclusion criteria comprised suspicion of Helicobacter pylori infection based on the presence of Helicobacter pylori antigen in the stool and/or characteristic macroscopic lesions seen on esophagogastroduodenoscopy.

Assessment of lead exposure in indoor shooters in central Poland.

A steady increase in shooting practices is observed worldwide. Potential lead exposure at shooting ranges poses a risk to their employees and users, which is not widely reported outside of the USA, especially in Poland. Exposure to lead results from the use of bullets containing lead and the main route of exposure to this metal at shooting ranges is inhalation, i.

Course of Plasmodium infection studied using 2D-COS on human erythrocytes.

Background: The threat of malaria is still present in the world. Recognizing the type of parasite is important in determining a treatment plan. The golden routine involves microscopic diagnostics of Giemsa-stained thin blood smears, however, alternative methods are also constantly being sought, in order to gain an additional insight into the course of the disease.

Blood-stage antiplasmodial activity and oocyst formation-blockage of metallo copper-cinchonine complex.

In the fight against malaria, the key is early treatment with antimalarial chemotherapy, such as artemisinin-based combination treatments (ACTs). However, has acquired multidrug resistance, including the emergence of strains with resistance to ACT. The development of novel antimalarial molecules, that are capable of interfering in the asexual and sexual blood stages, is important to slow down the transmission in endemic areas.

Impact of SARS CoV-2 /COVID-19 infection on the course of advanced chronic liver disease and hepatocellular carcinoma.

Background: About 20% of patients infected with SARS-CoV-2 develop COVID-19-the disease that has dominated health care in the last two years. The course of COVID-19 in patients with advanced liver disease tends to be severe, patients also suffer from a higher risk of complications and death. The primary object of this study was to assess the risk and causes of death in patients with cirrhosis and hepatocellular carcinoma (HCC).

Selected Properties of Self-Compacting Concrete with Recycled PET Aggregate.

In this paper, the issue of self-compacting concrete (SCC) with the addition of polyethylene terephthalate (PET) recycled aggregate is addressed. The PET utilized was a waste fraction in the PET-bottle-recycling process. The implementation of waste in concrete mixes has a positive impact on their environmental and social profile; however, technical requirements are not necessarily met.

Liver Injury in Patients with COVID-19 without Underlying Liver Disease.

Unlabelled: SARS-CoV-2 shows a high affinity for the ACE-2 receptor, present on the epithelial cells of the upper and lower respiratory tract, within the intestine, kidneys, heart, testes, biliary epithelium, and-where it is particularly challenging-on vascular endothelial cells. Liver involvement is a rare manifestation of COVID-19.

Material And Methods: We reviewed 450 patients admitted due to the fact of SARS-CoV-2 infection (COVID-19) including 88 with liver injury.

Biopolymers and Biomaterials for Special Applications within the Context of the Circular Economy.

The main challenge of the economy is counteracting the adverse effects of progressive industrialisation on the environment around the world. Economic development that accompanies this trend correlates to production increase in not only consumer articles but also special application articles that are difficult to remanufacture, such as medical supplies. For many researchers, discovering innovative materials for special applications that could become an essential element of circular economy production is important.

Urinary Tract Virome as an Urgent Target for Metagenomics.

Virome-a part of a microbiome-is a term used to describe all viruses found in the specific organism or system. Recently, as new technologies emerged, it has been confirmed that kidneys and the lower urinary tract are colonized not only by the previously described viruses, but also completely novel species. Viruses can be both pathogenic and protective, as they often carry important virulence factors, while at the same time represent anti-inflammatory functions.

X-ray CT Investigation of Bond Mechanism in Reinforced SCC Elements of Different Placement Technology.

The effect of different placing methods of the self-compacting concrete (SCC) mix-from the top and from the bottom of the form-on the bond failure mechanism was investigated within the scope of this paper. Existing studies regarding the known mechanisms of bond failure do not consider the bottom-up method of concrete placing, which improves the quality of the concrete microstructure around reinforcing bars. Background tests were performed on panel elements with dimensions of 800 × 480 × 160 mm.

Multilayer Casting of Eco-Efficient Self-Compacting Concrete with Reduced Binder Content.

In the study, experiments were performed on two eco-efficient self-compacting concrete mixes of reduced binder content containing supplementary cementitious materials. The behaviour of the eco-efficient self-compacting concrete (SCC) mixture was examined to determine whether it is suitable for multilayer casting. It is recommended that the SCC should be poured in an uninterrupted manner.

Hemophagocytic Lymphohistiocytosis Secondary to Peripheral T Cell Lymphoma with Rapid Onset and Fatal Progression in a Young Patient: A Case Report and Review of the Literature.

BACKGROUND Constant stimulation of lymphocytes and histiocytes can result in hemophagocytic lymphohistiocytosis (HLH), which can be primary or secondary (sHLH). The main causes of sHLH are infections and hematological malignancies, especially non-Hodgkin lymphoma. Despite new insights into the pathogenesis of HLH, the diagnosis and treatment of this immune disorder remain a great challenge.

A Comparison of the Composition of Selected Commercial Sandalwood Oils with the International Standard.

Sandalwood oils are highly desired but expensive, and hence many counterfeit oils are sold in high street shops. The study aimed to determine the content of oils sold under the name sandalwood oil and then compare their chromatographic profile and α- and β santalol content with the requirements of ISO 3518:2002. Gas chromatography with mass spectrometry analysis found that none of the six tested "sandalwood" oils met the ISO standard, especially in terms of α-santalol content.

Enhanced Biological Activity of a Novel Preparation of Essential Oil.

, one of the most popular medicinal plants, is the source of a bioactive essential oil characterized by a wide spectrum of biological activity, e.g., antiseptic, analgesic, and anticancer effects.

Active Thermography in Diagnostics of Timber Elements Covered with Polychrome.

The contribution of natural wood defects such as knots is an important factor influencing the strength characteristics of structural timber. This paper discusses the use of active thermography in the timber diagnostics, particularly in the determination of the knot area ratio (KAR) in elements covered with paint coatings. Moreover, on the basis of thermal images, the localization for the subsequent semi-destructive tests (SDTs) was established.

The Influence of the Drawing Process on the Mechanical Properties of TRIP Steel Wires with 0.4% C Content.

In the work, the results of the research concerned with the TRIP (Transformation Induced Plasticity) steel wire drawing process in experimental and theoretical ways are shown. The wire drawing process tests on the experimental way were conducted in both laboratories as well as industrial conditions, with the use of two drawing speeds (1.6 and 6 m/s) and two drawing schemes (low and high single reductions).

Eosinophilic Esophagitis in Children in North-Eastern Poland.

Background: An increase in the incidence of eosinophilic esophagitis worldwide is being observed in children. The aim of the study was to analyze the incidence, clinical manifestations, biochemical markers and endoscopic features of children with eosinophilic esophagitis in comparison to patients with non-eosinophilic esophagitis.

Methods: This single-center retrospective study included newly diagnosed children with eosinophilic (EoE) and non-eosinophilic (non-EoE) esophagitis based on endoscopic and histopathological results between January 2013 and December 2018.

Immunohistochemical markers for eosinophilic esophagitis.

Background And Aims: Eosinophilic esophagitis (EoE) is a chronic, local immune-mediated esophageal disease with eosinophil-dominated inflammation. The incidence of the disease is rapidly increasing in both children and adults. The pathogenesis of the disease is still not well understood.

Effect of Placement Technology on the Bond Strength Between Two Layers of Self-Compacting Concrete.

Self-compacting concrete (SCC) should generally be placed continuously, but it is not uncommon for contractors to be forced to use interruptions in concrete works due to delivery delays. The multilayer casting of SCC can cause weak bond conditions in the contact area of subsequent layers. Methods of preventing cold joint or lift line formation for normal concretes are not suitable for self-compacting concretes.

Selected predictors of maternal-fetal attachment in pregnancies with congenital disorders, other complications, and in healthy pregnancies.

Background: The mother-infant attachment begins to form during pregnancy and is important for the future development of the child. Pregnancy complications can affect this relationship. The purpose of the study was to identify predictors of maternal-fetal attachment in physiological and high-risk pregnancies.