Pulse wave parameters as a predictor of the development of post-transplant diabetes mellitus after kidney transplantation.

Background: Kidney transplantation is the preferred treatment for patients with end-stage renal disease, significantly preserving kidney function and patient quality of life. However, post-transplant diabetes mellitus (PTDM) is a common complication, occurring in approximately one-third of renal transplant recipients. This study aims to evaluate the role of pulse wave parameters in predicting PTDM and to identify other pre-transplant risk factors.

Association of selected adipokines with vitamin D deficiency in children with inflammatory bowel disease.

Background: Adipose tissue is significantly involved in inflammatory bowel disease (IBD). Vitamin D can affect both adipogenesis and inflammation. The aim of this study was to compare the production of selected adipokines, potentially involved in the pathogenesis of IBD - adiponectin, resistin, retinol binding protein 4 (RBP-4), adipocyte fatty acid binding protein and nesfatin-1 in children with IBD according to the presence of 25-hydroxyvitamin D (25(OH)D) deficiency.

Evaluation of Chemical and Morphological Properties of Spruce Wood Stored in the Natural Environment.

This paper focuses on the changes in chemical structure and fiber morphological properties of spruce wood during 15 months of its storage in an open forest woodshed. From the chemical composition, the extractives, cellulose, holocellulose, and lignin content were determined. The pH value was measured on the wood surface using a contact electrode.

Vascular Damage and Glycometabolic Control in Older Patients with Type 2 Diabetes.

Diabetes is one of the main risk factors for vascular damage, including endothelial dysfunction and arterial stiffness. The aim of this study was to compare selected parameters of vascular damage in patients with type 2 diabetes (T2D) in different age categories and to determine their relationship to indicators of glycometabolic control. A total of 160 patients with T2D were included in this cross-sectional study.

Relation of Chemical Composition and Colour of Spruce Wood.

The visual inspection of fresh cut spruce wood (, L. Karst.) showed the variability of its colour.

Dry-Matter Loss and Changes in the Chemical Composition of Spruce Wood after Long-Term Storing in the Form of Roundwood.

Wood stock in a warehouse is a necessary precondition for reliable manufacturing. However, wood can degrade and lose the matter during storage. "Dry-matter loss (DML)" is used to quantify the degradation following the changes in mass of a wood substance.

Changes in Chemical Structure of Thermally Modified Spruce Wood Due to Decaying Fungi.

Fungi play a critical role in the decomposition of wood and wood-based products in use. The ability of decaying fungi to cause degradation of polysaccharides and lignin in the thermally modified Norway spruce ( L. Karst.

Effect of Sunlight on the Change in Color of Unsteamed and Steamed Beech Wood with Water Steam.

This paper presents the differences in the color changes of unsteamed and steamed beech wood ( L.) caused by long-term exposure to sunlight on the surface of wood in interiors for 36 months. The light white-gray color of the yellow tinge of native beech wood darkened under the influence of sunlight, and the wood took on a pale brown color of yellow tinge.

Adiponectin, A-FABP and FGF-19 Levels in Women with Early Diagnosed Gestational Diabetes.

Background: Adiponectin, adipocyte fatty acid-binding protein (A-FABP), and fibroblast growth factor-19 (FGF-19) belong to proteins involved in glucose metabolism regulation. The aims of the study were to compare the plasma levels of these proteins in women with early diagnosed gestational diabetes mellitus (GDM) to those in healthy controls and to investigate their changes during pregnancy after early intervention. Methods: The study was undertaken as a case-control study.

Adipocytokines in Graves' orbitopathy and the effect of high-dose corticosteroids.

Graves' orbitopathy (GO) is a serious, progressive eye condition seen in patients with autoimmune thyroid disease. GO is characterized by inflammation and swelling of soft orbital tissues. Adipose tissue produces cytokine mediators called adipokines.

Hypertriglyceridemic Waist in Patients with Type 2 Diabetes: Its Relationship to Selected Markers of Vascular Damage.

To evaluate the association between hypertriglyceridemic waist (HTGW), a promising marker of visceral adiposity and cardiovascular (CV) risk, and different indicators of vascular damage in type 2 diabetes (T2D) patients. This case-control study included 161 patients with T2D (91 males, 70 females) and 40 healthy controls (24 males, 16 females). HTWG was defined as waist circumference >90 cm in men or >85 cm in women and triglyceride concentrations >2 mmol/L.

Chemical and Morphological Composition of Norway Spruce Wood (, L.) in the Dependence of Its Storage.

Chemical composition and morphological properties of Norway spruce wood and bark were evaluated. The extractives, cellulose, hemicelluloses, and lignin contents were determined by wet chemistry methods. The dimensional characteristics of the fibers (length and width) were measured by Fiber Tester.

Role of Adipose Tissue in Inflammatory Bowel Disease.

Inflammatory bowel diseases (IBDs), chronic inflammatory disorders affecting the gastrointestinal tract, include Crohn's disease and ulcerative colitis. There are increasing clinical and experimental data showing that obesity, especially visceral adiposity, plays a substantial role in the pathogenesis of IBD. Obesity seems to be an important risk factor also for IBD disease severity and clinical outcomes.

Retinal oxygen saturation is associated with HbA1c but not with short-term diabetes control, internal environment, smoking and mild retinopathy - ROXINEGLYD study.

Purpose: Purpose of this prospective uncontrolled single-centre pilot study was to find an association of retinal oxygen saturation (SatO ) with acid-base balance (ABB), carboxyhaemoglobin concentration, current plasma glucose concentration (PG), mean PG and PG variability over the last 72 hr, haemoglobin A1c (HbA1c), and other conditions.

Methods: Forty-one adults (17 men) with type 1 (N = 14) or type 2 (N = 27) diabetes mellitus, age 48.6 ± 13.

Physicochemical Properties of Biobutanol as an Advanced Biofuel.

Biobutanol is a renewable, less polluting, and potentially viable alternative fuel to conventional gasoline. Biobutanol can be produced from same sources as bioethanol, and it has many advantages over the widespread bioethanol. This paper systematically analyzes biobutanol fuel as an alternative to bioethanol in alcohol-gasoline mixtures and the physicochemical properties.

Determination of Tractor Engine Oil Change Interval Based on Material Properties.

This article focuses on the issue of motor oils used in the engines of non-road mobile machinery (NRMM), more specifically tractors. The primary goal of the paper is to determine the appropriate replacement interval for these oils. The physical properties of the examined samples were first determined by conventional instruments.

Host responses and metabolic profiles of wood components in Dutch elm hybrids with a contrasting tolerance to Dutch elm disease.

Background And Aims: Changes occurring in the macromolecular traits of cell wall components in elm wood following attack by Ophiostoma novo-ulmi, the causative agent of Dutch elm disease (DED), are poorly understood. The purpose of this study was to compare host responses and the metabolic profiles of wood components for two Dutch elm (Ulmus) hybrids, 'Groeneveld' (a susceptible clone) and 'Dodoens' (a tolerant clone), that have contrasting survival strategies upon infection with the current prevalent strain of DED.

Methods: Ten-year-old plants of the hybrid elms were inoculated with O.

The effect of heme oxygenase on ganglioside redistribution within hepatocytes in experimental estrogen-induced cholestasis.

Cholestasis is characterized by the elevation of serum total bile acids (TBA), which leads to the production of both free radicals and oxidative stress. Although they do not share the same mechanisms, membrane glycosphingolipids (GSL) and the antioxidant enzyme heme oxygenase-1 (HMOX1) both act against the pro-oxidative effect of TBA. The aim of the study was to assess the role of HMOX on GSL redistribution and composition within hepatocytes in the rat model of estrogen-induced cholestasis.

Leaf trait dissimilarities between Dutch elm hybrids with a contrasting tolerance to Dutch elm disease.

Background And Aims: Previous studies have shown that Ophiostoma novo-ulmi, the causative agent of Dutch elm disease (DED), is able to colonize remote areas in infected plants of Ulmus such as the leaf midrib and secondary veins. The objective of this study was to compare the performances in leaf traits between two Dutch elm hybrids 'Groeneveld' and 'Dodoens' which possess a contrasting tolerance to DED. Trait linkages were also tested with leaf mass per area (LMA) and with the reduced Young's modulus of elasticity (MOE) as a result of structural, developmental or functional linkages.

[Amplification and overexpression of HER-2/neu in parotid gland salivary duct carcinoma. Immunohistochemical study and fluorescence in situ hybridization].

Salivary duct carcinoma (SDC) is highly malignant salivary gland tumour with aggressive clinical behaviour, characterised by its histological resemblance to invasive ductal carcinoma of the breast. Amplification of gene HER-2/neu and overexpression of its gene product have been shown to have both prognostic and treatment implications in breast cancer. The reports concerning the expression of c-erbB2/HER-2/neu in salivary gland tumours are few and controversial.

Expression of HER-2/neu gene and protein in salivary duct carcinomas of parotid gland as revealed by fluorescence in-situ hybridization and immunohistochemistry.

Aims: Salivary duct carcinoma is a highly malignant salivary gland tumour with aggressive clinical behaviour, characterized by histological resemblance to invasive ductal carcinoma of the breast. Amplification of HER-2/neu oncogene and over-expression of its gene product have both prognostic and therapeutic implications in breast cancer. Recent report on salivary duct carcinomas for HER-2/neu using immunohistochemistry (IHC) has shown over-expression in most cases.

[Long-term follow-up of patients with extensive ulcerous colitis with emphasis on the occurrence of dysplastic changes and colorectal carcinoma].

The chronic course of idiopathic intestinal inflammations is characterized also by a relatively high incidence of complications, local ones affecting the entire large intestine, as well as extraintestinal ones in remote organs. In the submitted paper the authors present the results of a six-year follow-up focused on the incidence of dysplastic changes of the intestinal mucosa and colorectal carcinoma in 46 patients from a group of 220 patients followed up on a long-term basis at the Second Medical Clinic of the Faculty Hospital and Medical Faculty Olomouc because of the extensive type of ulcerative colitis. The incidence of these complications is not high in our group and is only slightly higher than in the general population.

Spindle cell myoepithelial tumours of the parotid gland with extensive lipomatous metaplasia. A report of four cases with immunohistochemical and ultrastructural findings.

We report four cases of parotid gland tumours composed predominantly of spindle-shaped myoepithelial cells and mature adipocytes. The central portion of one tumour showed extensive adipose differentiation, whereas in the peripheral parts there were small foci of ductal epithelium arranged in cords and tubules within an abundant myxoid stroma. The other cases were adipose spindle cell myoepitheliomas without an obvious glandular component.

Salivary duct carcinoma--a highly aggressive salivary gland tumor with HER-2/neu oncoprotein overexpression.

Salivary duct carcinoma (SDC) is a highly malignant salivary gland tumor with aggressive clinical behavior, and is characterized by its histological resemblance to invasive ductal carcinoma of the breast. Overexpression and/or amplification of proto-oncogene Her2/neu has been shown to influence both prognosis and treatment of breast cancer. Since salivary duct carcinoma and ductal breast carcinoma share many common characteristics, HER2/neu overexpression might also be important in SDC.

Depression of experimental gastric ulcers and acute pancreatitis in rats treated by 5-azacytosine, 5-azacytidine and their N-methyl derivatives.

5-Azacytosine, 1-methyl-5-azacytosine and 5-azacytidine administered to rats with a ligated pylorus block gastric secretion, gastric acidity, the extent of hemorrhage and the number and size of gastric defects. The same drugs also depress the development of experimental acute pancreatitis mediated in rats by interstitial administration of 7.5% natrium cholate into the pancreas in vivo.