Green light enabled Staudinger-Bertozzi ligation.

We introduce a visible light-induced Staudinger-Bertozzi ligation photo-uncaging of a triphenylphosphine moiety with a photolabile coumarin derivative. Our action plot study examines the conversion as the function of wavelength, revealing that the uncaging process and Staudinger reaction can be triggered by green light ( < 550 nm). We further demonstrate the applicability of our approach in materials science endgroup modification of water soluble poly(ethylene glycol) and green light-induced patterning of a solid substrate.

Modular functionalization and hydrogel formation red-shifted and self-reporting [2+2] cycloadditions.

We present a modularly applicable, red-shifted and self-reporting photodynamic covalent crosslinker, abbreviated qStyPy, that performs [2+2] cycloadditions upon irradiation with 470 nm in water. The rational design of qStyPy increases its hydrophilicity due to a permanent charge and features a broad emission in the far-red/near-infrared regime as a readout for the cycloadduct formation, rendering qStyPy suitable for biomedical applications.

Green light triggered [2+2] cycloaddition of halochromic styrylquinoxaline-controlling photoreactivity by pH.

Photochemical reactions are a powerful tool in (bio)materials design due to the spatial and temporal control light can provide. To extend their applications in biological setting, the use of low-energy, long wavelength light with high penetration propertiesis required. Further regulation of the photochemical process by additional stimuli, such as pH, will open the door for construction of highly regulated systems in nanotechnology- and biology-driven applications.