Publications by authors named "Kubra Hacieminoglu Ulker"
[Investigation of O25b-ST131 Clone Frequency and Presence of Carbapenem and Fosfomycin Resistance Genes in Escherichia coli Isolates: First Detection of fosA3 from Escherichia coli O25bSTf131 Clone from Türkiye].
Mikrobiyol Bul
July 2023
Article Synopsis
- The Escherichia coli ST131 clone, identified as a 'high-risk pandemic clone' since 2008, significantly contributes to the global spread of antimicrobial resistance and carries genes for both virulence and antibiotic resistance.
- A study investigated the prevalence of the O25b-ST131 clone and the presence of antibiotic resistance genes in fluoroquinolone-resistant E.coli isolates from urine samples, using specific PCR methods for detection.
- Results showed that 51.2% of isolates were identified as E.coli O25b-ST131, with carbapenem and fosfomycin resistance rates at 3.41%, and specific resistance genes detected in some isolates, highlighting the concerning rise in antibiotic resistance.
Objective: Urinary tract infections are one of the most common causes of morbidity around the world. Fosfomycin is a specific broad-spectrum antibiotic used to treat these infections. However, in recent years, many studies have reported increased fosfomycin resistance in Enterobacterales isolates.
View Article and Find Full Text PDFCarbapenem-resistant (CRE) have become a growing problem worldwide in recent years. Options for the treatment of CRE are limited and one of these options is gentamicin. For this reason, gentamicin susceptibility should be properly determined.
View Article and Find Full Text PDFContext: Isepamicin is a new semisynthetic aminoglycoside derived from gentamicin B and it is effective against Gram negative bacteria. Antibiotic resistance is an emerging problem and new options need for the treatment of infections caused by Gram negative bacteria.
Aims: In this study we aimed to investigate the in vitro efficiency in carbapenem susceptible and nonsusceptible Enterobacterales and Pseudomonas aeruginosa.