Clinical spectrum of primary hemophagocytic lymphohistiocytosis: experience of reference centers in Central and Southeast Anatolia.

Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening disease, with a high mortality if left untreated. In addition, the disease has unique diagnostic challenges. Therefore, despite the existing guidelines on management, current clinical practice data is informative on the course and outcome.

Peak expiratory flow, core performance and physical activity in normal-weight, overweight, and obese adolescents.

The objectives of this study were to (1) compare peak expiratory flow (PEF), physical activity (PA), and core performance among normal-weight, overweight, and obese adolescents and (2) explore the relationships between PEF, physical activity, core performance, and anthropometric measurements across these groups. Ninety adolescents aged 10-13 yr were categorized based on BMI: normal weight (n = 30, 5th to < 85th percentile, BMI-Z score -2 to < 1), overweight (n = 30, 85th to < 95th percentile, BMI-Z score 1 to < 2), and obese (n = 30, > 95th percentile, BMI-Z score > 2). PEF and percent-predicted values of PEF (PEF% pred) values were calculated.

The effects of using heel protectors on the prevention of heel pressure injuries and plantar flexion contractures.

Background: Immobilization in the intensive care unit can lead to pressure injuries and plantar flexion contractures.

Aim: This study was conducted to evaluate the effectiveness of heel protectors applied for the prevention of heel pressure injuries and plantar flexion contractures in intensive care units.

Methods: This study was conducted as a randomized controlled trial in two adult intensive care units of a teaching and research hospital.

Engineering Acetobacterium woodii for the production of isopropanol and acetone from carbon dioxide and hydrogen.

The capability of four genetically modified Acetobacterium woodii strains for improved production of acetone from CO and hydrogen was tested. The acetone biosynthesis pathway was constructed by combining genes from Clostridium acetobutylicum and Clostridium aceticum. Expression of acetone production genes was demonstrated in all strains.

Autotrophic (C-gas) versus heterotrophic (fructose) accumulation of acetic acid and ethanol in Clostridium aceticum.

The influence of the carbon source on the metabolism and growth of Clostridium aceticum was investigated, supplying either CO or fructose as sole carbon source. The acid and solvent production patterns were determined under either autotrophic or heterotrophic conditions, elucidating the effect of pH on the substrate's bioconversion pattern. The highest maximum specific growth rate was observed with CO, under the organism's optimal growth conditions, reaching 0.

The Quality of Life, Depression Levels and Coping Styles of Patients on Kidney Transplant Waiting List.

This study aims to understand the coping strategies, depression levels, sociodemographic characteristics of Turkish patients with hemodialysis, and the other factors explain quality of life levels. This research is a cross-sectional study. The convenience sampling consisted of 292 patients with hemodialysis.

Familial Mediterranean Fever with Neonatal Onset: Case Report.

Familial Mediterranean fever (FMF) is an autosomal recessively inherited disorder characterized by recurrent fever and attacks of abdominal pain, chest pain, and joint pain. Attacks of recurrent fever and serositis are encountered clinically. Attacks may present either with only one symptom or many simultaneous symptoms.

Solventogenesis in Clostridium aceticum producing high concentrations of ethanol from syngas.

The ethanol production capability of Clostridium aceticum was investigated and optimized, in order to evaluate the ability of that organism to produce high concentrations of fuel-ethanol. The results showed that C. aceticum can produce significant amounts of ethanol when a natural pH drop occurs in the fermentation broth as a consequence of acetic acid production in a first stage.