Silent Sinus Syndrome.

Silent sinus syndrom is rare and slow progressive disorder associated with asymptomatic chronic maxillary sinusitis and collapse of the orbital floor. The most common manifestations are enophtalmos, hypoglobus and pseudoretraction upper eyelid. Silent sinus syndrome is almost a unilateral condition and is usually diagnosed in patients in their 30´s and 40´s.

The utility of massively parallel sequencing for posterior polymorphous corneal dystrophy type 3 molecular diagnosis.

The aim of this study was to identify the molecular genetic cause of disease in posterior polymorphous corneal dystrophy (PPCD) probands of diverse origin and to assess the utility of massively parallel sequencing in the detection of ZEB1 mutations. We investigated a total of 12 families (five British, four Czech, one Slovak and two Swiss). Ten novel and two recurrent disease-causing mutations in ZEB1, were identified in probands by Sanger (n = 5), exome (n = 4) and genome (n = 3) sequencing.

[ProVens® in the Therapy of Glaucoma and Ocular Hypertension].

Objective: To assess the effect of the ProVens® dietary supplement administration on intraocular pressure in patients with glaucoma and ocular hypertension.

Material And Methods: The patients included in the trial were given the ProVens® dietary supplement once daily. One ProVens® tablet contains: 50 mg of maritime pine bark extract, 100 mg of green tea extract, and 3 mg of blueberry extract.

Analytic methods in assessment of optic nerve cupping.

The intent of this paper is to provide a systems-based analysis of the methods used to evaluate optic nerve cupping, identify potential flaws in these systems, and propose alternatives better to assess this anatomic quantity. Estimation of optic nerve cupping requires an analytic understanding of both the psychophysical as well as the mathematical bases inherent in this measure. When the (decimal-based) cup-to-disc ratio is used to quantitate optic nerve cupping, a one-dimensional, linear estimate is produced, which in turn is derived from two- or three-dimensional, non-linear physical quantities of area or volume, respectively.

Thickness related textural properties of retinal nerve fiber layer in color fundus images.

Images of ocular fundus are routinely utilized in ophthalmology. Since an examination using fundus camera is relatively fast and cheap procedure, it can be used as a proper diagnostic tool for screening of retinal diseases such as the glaucoma. One of the glaucoma symptoms is progressive atrophy of the retinal nerve fiber layer (RNFL) resulting in variations of the RNFL thickness.

Analysis of visual appearance of retinal nerve fibers in high resolution fundus images: a study on normal subjects.

The retinal ganglion axons are an important part of the visual system, which can be directly observed by fundus camera. The layer they form together inside the retina is the retinal nerve fiber layer (RNFL). This paper describes results of a texture RNFL analysis in color fundus photographs and compares these results with quantitative measurement of RNFL thickness obtained from optical coherence tomography on normal subjects.

[Statistical analysis of the nerve fiber layer in color digital images of the retina].

The topic of the article is to inform about the analysis of the nerve fiber layer in color digital images of the retina. The study group consists of 11 eyes (9 patients) with marked focal losses in the nerve fiber layer of the retina. The control group consists of 14 eyes (7 patients).

[Digital images of the retinal nerve fiber layer in healthy eye and in glaucoma].

The authors describe the procedure how to take pictures of the retinal nerve fiber layer with the fundus camera CANON CF-60UV connected to the digital camera EOS 20D. They attach practical instructions how to modify taken digital pictures with the Photoshop CS2 software, to make the nerve fiber layer and its losses more visible. They present modified pictures of the nerve fiber layer in healthy eye and in glaucoma where the losses are compared to the scotomas in the visual field.

[Subjective examination of the nerve fiber layer of the retina and its evaluation in a healthy eye and in glaucoma].

The authors describe the advantage of subjective examination of the nerve fiber layer in everyday outpatient praxis of the ophthalmologist. The objective examination of the nerve fiber layer is performed on specialized clinics by means of expensive instruments as are OCT, GDX or HRT. Every ophthalmologist may analyze the retinal nerve fiber layer subjectively with the basic equipment of the praxis.

[Adenoma of the pituitary gland in the ophthalmologist's out-patient practice].

Authors describe eye and general symptoms in five patients with the adenoma of the pituitary gland, detected on the results of the ophthalmological examination. Identical symptoms in all patients were the decrease of central visual acuity or visual field defects. The general somatic manifestations of the disease were different.

[Influence of intracranial pressure decrease in the pseudotumor cerebri syndrome on visual function].

Authors describe ocular and neurological findings in a 68 years old female patient with the intracranial hypertension (pseudotumor cerebri). For developing edema of the optic nerve head on the fundus (oedema papillae), accompanied with lowered visual acuity and visual field defects, an urgent surgical treatment was indicated--the lumboperitoneal shunt was introduced. After the operation, although the atrophy of the optic nerve head atrophy occurred, the visual acuity was maintained and visual fields sensitivity improved.

[Effect of TLT absorptive eyeglasses on progression of myopia in children].

The incidence of myopia is increasing worldwide. At the last VIIIth international conference on myopia held in June 2000 in Boston attention was aroused by the work of Quin et al. on the influence of noctural illumination in rooms where children slept on their subsequent development of myopia.

[Clinical features and therapy of giant cell temporal arteritis].

Giant-cell temporal arteritis is an urgent condition in ophthalmology as successful treatment depends on early diagnosis and effective therapy before the development of ophthalmological symptoms. The authors investigated on a long-term basis five patients. In the first one complete regression of general and ocular symptoms occurred and vision was preserved.

[Methods in optic nerve disk digital planimetry].

The authors define the term planimetry in general and planimetry of the optic disc in particular and present a brief review of the history of planimetric evaluation of the optic disc. They describe a digital analyzer of their own design, the method of examination of the optic disc and further processing and recording of data. They define the indications and contraindications of examination, summarize the asset and limitations of the method used.

[The optic nerve disk in myopic children with elevated intraocular pressure].

The optic nerve disc of short-sighted children with elevated intraocular pressure was investigated to achieve early assessment of glaucoma and to detect signs which differentiate changes in the disc caused by short-sightedness from changes caused by glaucoma. The authors examined 16 eyes of 8 short-sighted children with elevated intraocular pressure. In addition to the basic ophthalmological examination they made a digital analysis of the optic nerve disc incl.

[Effect of infrared rays on the eye in progressive myopia].

In the submitted paper the authors pay attention to infrared radiation close to visible light is intensely absorbed by haemoglobin, melanin and xanthophyll whereby part of the radiation energy is transformed into heat. The authors present three series of experiments where they investigated by different methods changes in the vitreous body after exposure to light, infrared radiation or raised temperature. They assume that on the defocused eye with a myopic conus which developed as a result of an inborn inadequate closure of the optic cup the light can cause a rise of temperature in the vitreous body.

[Functional disorders of the visual field].

The author describes a group of 12 patients with concentric narrowing of the visual field which was not elucidated, with the exception of one patient, even after all indicated clinical and paraclinical examinations. He describes diagnostic methods providing evidence of the functional character of the impaired visual field and presents typical findings of changes of the visual field in functional disorders.

[Visual perceptions in ophthalmic migraine].

The number of patients with ophthalmic migraine is steadily increasing. The symptoms of their attacks are dominated by typical visual aura, followed by major or minor headache. The authors present the experience of three physicians who observed the symptoms on themselves.