Publications by authors named "Kuanrong Dang"

Article Synopsis
  • The study analyzes 20 years of research on anterior segment optical coherence tomography (AS-OCT) in glaucoma using bibliometric methods to identify research trends and hotspots.
  • A total of 931 articles were reviewed, revealing that the US, China, and Singapore are the leading contributors to this research, with significant collaboration among these countries.
  • Key journals, such as the Journal of Glaucoma and Investigative Ophthalmology & Visual Science, published the most articles, while important keywords in the field include deep learning, classification, and management.
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Article Synopsis
  • * Endoscopic cyclophotocoagulation (ECP) is a key treatment method that works by reducing the production of aqueous humor through the coagulation of the ciliary body, and has been in use since the 1990s.
  • * The review discusses the technology used in ECP, its effectiveness compared to other treatments, its current clinical use, possible postoperative complications, and how ECP’s role in glaucoma treatment is expected to grow and adapt with new advancements.
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Article Synopsis
  • ICL surgery is a growing refractive surgery option known for providing stable and high-quality visual outcomes, complementing existing corneal refractive techniques.
  • A bibliometric analysis of 875 studies from 1996 to 2023 highlighted trends, with China leading in publication volume and significant contributions from institutions like Fudan University and Kitasato University.
  • Key research themes emerged around topics such as "visual quality," "refractive surgery," and "high myopia," with high-impact articles primarily focusing on the safety and efficacy of ICL procedures.
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Article Synopsis
  • The article reviews potential complications related to intraocular pressure (IOP) after Implantable Collamer Lens (ICL) surgery for myopia correction.
  • It highlights common issues like residual viscoelastic, steroid response, and excessive vault of the ICL that can lead to elevated IOP, and discusses their causes, impact, and management strategies.
  • Rare complications such as Toxic Anterior Segment Syndrome and Urrets-Zavalia Syndrome are also examined to provide a comprehensive understanding and guidance for eye care professionals to ensure optimal patient care.
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Aim: To assess the efficacy versus the adverse effects of various concentrations of atropine in the prevention of myopia in Asian children.

Methods: Databases (PubMed, EMBASE, the Cochrane Library and Web of science) were comprehensively searched from inception to April 2022. Types of studies included were randomized clinical trials (RCTs).

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Age-related macular degeneration (AMD) is the most common blindness-causing disease among the elderly. Under oxidative stress, low-density lipoprotein in the outer layer of the retina is easily converted into oxidized low-density lipoprotein (OxLDL), which promotes the development of choroidal neovascularization (CNV), the main pathological change in wet AMD. Liver X receptor (LXR), a ligand-activated nuclear transcription factor, regulates various processes related to CNV, including lipid metabolism, cholesterol transport, inflammation, and angiogenesis.

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Metformin (MET), a first-line oral agent used to treat diabetes, exerts its function mainly by activating adenosine monophosphate-activated protein. The accumulation of oxidized phospholipids in the outer layer of the retina plays a key role in retinal pigment epithelium (RPE) cells death and the formation of choroidal neovascularization (CNV), which mean the development of age-related macular degeneration (AMD). Recent studies have shown that MET can regulate lipid metabolism, inhibit inflammation, and prohibit retinal cell death and CNV formation due to various pathological factors.

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Aim: To investigate whether intravitreal injection of oxidized low-density lipoprotein (OxLDL) can promote laser-induced choroidal neovascularization (CNV) formation in mice and the mechanism involved, thereby to develop a better animal model.

Methods: C57BL6/J mice were randomized into three groups. Immediately after CNV induction with 532 nm laser photocoagulation, 1.

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