Publications by authors named "Kuang-Nan Hsu"

Background: To update the characteristics of patients with Alzheimer's disease (AD) and their informants in Taiwan and compare them from 12 years ago.

Methods: 1218 patients with AD and their informants were recruited from six hospitals in Taiwan. The uniform data set version 3.

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  • The study investigates the relationship between the GP.Mur red blood cell type and blood pressure, specifically how it may influence blood pressure levels in adults.
  • Researchers analyzed data from 989 non-elderly adults, focusing on factors like BMI, age, and hemoglobin levels to determine their impact on blood pressure.
  • Results showed GP.Mur slightly increased systolic blood pressure, particularly in non-anemic Taiwanese men, but the contribution of GP.Mur to blood pressure was both hemoglobin-dependent and independent, with further research needed to fully understand its mechanisms.
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Background: This study intended to investigate whether etiological stroke subtypes and their corresponding major risk factors have differential effects on outcomes between genders.

Patients And Methods: We enrolled 403 consecutive patients with first-ever acute ischemic stroke (170 women, 233 men), from a referral hospital in Taiwan over a 2-year period. Gender differences in demographics, vascular risk factors, access to health care, etiological stroke subtypes, stroke severity, and outcomes were examined.

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  • The study investigates the role of mitochondrial DNA (mtDNA) variations in predicting type 2 diabetes (T2D) among men and women, particularly in relation to ischemic stroke (IS).
  • A matched case-control design involved 373 T2D patients and 327 healthy individuals, analyzing mtDNA haplogroups and conducting functional tests on a subset of participants.
  • Results indicated specific mtDNA haplogroups (B4a1a, E2b1) are linked to T2D risk, highlighting a higher susceptibility in men and the influence of age on IS occurrence, while pointing to the need for deeper understanding of mitochondrial function in T2D development.
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Background: Acute disseminated encephalomyelitis (ADEM) is a monophasic demyelinating disease of the central nervous system, typically occurring after infections or vaccinations. To our knowledge, scrub typhus has not been described in association with ADEM.

Case Report: A 77-year-old man was admitted with fever, convulsions and an altered level of consciousness.

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