Publications by authors named "Kuang Ling"

In this work, we consider the waveform design for radar systems based on orthogonal time-frequency space (OTFS). The conditional mutual information (CMI), chosen as a promising metric for assessing the radar cognitive capability, serves as the criterion for OTFS waveform design. After formulating the OTFS waveform design problem based on maximizing CMI, we propose an equivalent waveform processing approach by minimizing the autocorrelation sidelobes and cross-correlations (ASaCC) of the OTFS transmitting matrix.

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Experimental studies have indicated that exposure to disinfection byproducts (DBPs) may affect the lipid synthesis. However, epidemiological evidence is sparse. This study aimed to investigate the relationship between blood trihalomethane (THM) exposure and the risk of dyslipidemia from the National Health and Nutrition Examination Survey 2005-2018.

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: The causal association of specific gut microbiota with dementia remains incompletely understood. We aimed to access the causal relationships in which one or more gut microbiota account for dementia. : Using data from the MiBioGen and FinnGen consortia, we employed multiple Mendelian randomization (MR) approaches including two-sample MR (TSMR), multivariable MR (MVMR), and Bayesian model averaging MR to comprehensively evaluate the causal associations between 119 genera and dementia, and to prioritize the predominant bacterium.

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Porcine epidemic diarrhea virus (PEDV) poses a significant threat to pigs, with piglets under seven days old facing a mortality rate of up to 100 %. This study aimed to explore the maturation of the immune system in piglets across different age groups and their corresponding immune responses to PEDV infection. Real-time quantitative PCR was employed to assess the relative mRNA expression of inflammation-related factors in infected pigs compared to non-infected counterparts at varying ages.

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The causal association of circulating metabolites with dementia remains uncertain. We assessed the causal association of circulating metabolites with dementia utilizing Mendelian randomization (MR) methods. We performed univariable MR analysis to evaluate the associations of 486 metabolites with dementia, Alzheimer's disease (AD), and vascular dementia (VaD) risk.

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Background: Equine herpesvirus type 1 (EHV-1) is commonly associated with horse abortion. Currently, there are no reported cases of abortion resulting from EHV-1 infection in donkeys.

Results: This was the first survey-based study of Chinese donkeys.

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Kirkovirus (kirV), a seemingly novel virus family, has been found in horses and donkeys. The study's objectives are to investigate the presence of the virus in swine. In this study, donkey-like kirV was detected in rectal swabs of piglets with diarrhea, and the positive rate was found to be 100% (149/149).

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Background: Varicellovirus equidalpha1 (formerly Equid alphaherpesvirus 1, EqAHV-1) is among the most important viruses responsible for respiratory disease outbreaks among horses throughout the world. No reports to date have detailed the association between EqAHV-1 and respiratory disease among horses in China. This study described one such outbreak among a population of horses in north Xinjiang that occurred from April 2021 - May 2023.

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Background: The relationship between whole grain intake and chronic kidney disease (CKD) remains uncertain.

Objective: This study aimed to evaluate the association between whole grain intake and risk of CKD in Chinese adults.

Methods: The present cross-sectional study used data from the China Health and Nutrition Survey conducted in 2009.

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Nine different species of Equus caballus papillomavirus (EcPV) and three bovine papillomaviruses (BPVs) have been reported to infect horses. However, there are few descriptions of such infections in China. In our pioneer study on Chinese horses, we identified EcPV-2 in the nasal swabs (4/230, 1.

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Article Synopsis
  • A new virus family, tentatively named Kirkoviridae, has been discovered in a diseased horse in the USA, suggesting the need for its classification as an official family.
  • The viruses in this family are larger than typical Circoviridae, with genomes around 4000 nucleotides and additional unknown protein-coding regions.
  • Recent research in China identified similar kirkovirus-like viruses in donkey excretes, with 8 out of 73 samples testing positive, leading to full genomic sequencing of three viruses and partial sequencing of others.
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Background: EHV-1 is one of the most serious viral pathogens that frequently cause abortion in horses around the world. However, so far, relatively little information is available on EHV-1 infections as they occur in China. In January 2021, during an abortion storm which occurred in Yili horses at the Chinese State Studs of Zhaosu (North Xinjiang, China), 43 out of 800 pregnant mares aborted.

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Background: Diabetes is a common metabolic disease with an increasing incidence in middle-aged and elderly people in recent years. Chronic hyperglycemia is the basic feature of diabetes, which can cause long-term damage to eyes, kidneys, nerves, heart, and blood vessels, resulting in functional decline or even failure. Glycosylated hemoglobin (HbA1c) can be used as an indicator of an individual's blood sugar status over the past 3 months; however, it is slightly affected by ischemic anemia.

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Background: To analyze the relationship between the peripheral blood absolute lymphocyte count (ALC)/absolute monocyte count (AMC) ratio, soluble interleukin 2 receptor (sIL-2R) level, serum programmed cell death 1 (PD-1) level, and the prognosis of patients with diffuse large B-cell lymphoma (DLBCL).

Methods: A total of 78 patients with DLBCL admitted to hospital and 30 healthy controls were enrolled as the case group and control group between August 2019 and June 2020, respectively. The ALC/AMC ratio and the levels of sIL-2R and serum PD-1 between the 2 groups and among patients with different prognoses were compared.

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Multiple novel circular replication-associated protein (Rep)-encoding single stranded (CRESS) DNA viruses have been extensively identified in the feces of humans and animals. Here, we first detected CRESS DNA virus (named Horse-CRESS DNA-like virus, HCLV) in two fecal samples from 10 imported thoroughbred (TB) horses in the customs quarantine station in North Xinjiang province, China. Additionally, we found that this virus was not detected in local breeds (LBs) (0/41) and was found only in imported TB horses (2/73).

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Article Synopsis
  • In November 2018, a respiratory disease outbreak in foals at a Changji equestrian club prompted an investigation using viral metagenomics to identify possible pathogens.
  • The study found that equid herpesviruses EHV-2, EHV-4, and EHV-5 were present, with the foals showing coinfection, particularly with EHV-4 and EHV-5.
  • Analysis of nasal swabs from healthy thoroughbred foals and horses showed a 9.9% prevalence of EHV-5 and a 1.5% prevalence of EHV-2, with EHV-4 absent, indicating that multiple herpesviruses circulate in China and suggesting EHV-4's role
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Hyaluronic acid injection is becoming a popular way for penile augmentation. However, only few studies and follow-ups have investigated the various complications of hyaluronic acid injection and their corresponding management. In this study, a total of 230 patients who had penile augmentation with hyaluronic acid injection from January 2018 to December 2019 were examined on follow-up for penile girth, complications, and their corresponding management.

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In recent years, nursing has come to be considered a high-risk and high-pressure profession, given the fast-paced working environment and constant need to handle emergencies, especially for nurses working in hemodialysis centers. Nearly every day, nurses are confronted with life and death situations and are required to provide skilled, high quality care for their patients, in fast-paced and demanding environments. Thus, nurses are susceptible to both psychological stress and other mental health problems, making them more vulnerable to burnout when compared against other healthcare professions.

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To study the prevalence of burnout and job satisfaction in Chinese pediatrics residents.Prospective participants were invited via a WeChat group to participate from October 1, 2018 to January 31, 2019. The Maslach Burnout Inventory-Human Services Survey was used to measure physician burnout, and the Minnesota Satisfaction Questionnaire was used to measure job satisfaction.

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Article Synopsis
  • An 8-year-old thoroughbred mare died at an equestrian club in Xinjiang, China, after facing health issues post-foaling.
  • Researchers identified a new virus, "kirkovirus Cj-7-7," from the mare's fecal virome, indicating it is related to other known viruses in the Kirkoviridae family.
  • The study underscores the genetic variation and spread of Kirkoviruses, highlighting the presence of this specific virus among horses in northern Xinjiang.
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In 2015, a novel equine parvovirus, equine parvovirus-cerebrospinal fluid (EqPV-CSF), was identified from cerebrospinal fluid of a horse with neurological signs and lymphocytosis in USA. In our study, an EqPV-CSF-like virus was detected from 15 serum samples of 65 imported thoroughbred horses during custom quarantine in north Xinjiang province, China. Further field investigation in several major horse-producing areas in Xinjiang using specific PCR showed that this virus was detected mainly in thoroughbred horses (39/154 positive) previously imported, not in local breeds (0/127 positive).

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Until now, no reliable method is recognised in treating buried penis. This study explored a new method of penile length augmentation using acellular dermal matrix filler in infrapubic space combined with liposuction and penile suspensory release. Patients with "small-sized penis" received penile length augmentation procedure including suprapubic liposuction, penile suspensory ligament release and insertion of folded acellular dermal matrix between corpora cavernosa and pubis symphysis.

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Infections with bovine viral diarrhea virus (BVDV) contribute significantly to health-related economic losses in the beef and dairy industries and are widespread throughout the world. Severe acute BVDV infection is characterized by a gastrointestinal (GI) inflammatory response. The mechanism of inflammatory lesions caused by BVDV remains unknown.

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Background: Alveolar echinococcosis (AE) is a life-threatening human disease caused by Echinococcus multilocularis transmitted between rodents and dogs/foxes in the Northern Hemisphere. The study aims to identify the genetic variation of the parasite in AE patients from China.

Methods: E.

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