Publications by authors named "Kuang H Kang"
Article Synopsis
- The study investigates where very low birth weight (VLBW) neonates in the U.S. receive surgical care, focusing on the presence of specialized pediatric surgery (PS) and anesthesia (PA) at different centers.
- Researchers analyzed data from over 24,000 VLBW neonates and found that a significant majority (85.9%) had surgery at centers equipped with both PS and PA.
- The study highlights the need for more research to understand why some VLBW neonates are treated at centers lacking these pediatric specialists, despite the proven benefits of having them on staff.
Article Synopsis
- This study focused on spontaneous intestinal perforation (SIP) in very-low-birth-weight (VLBW) neonates, comparing its mortality rates to those of necrotizing enterocolitis (NEC).
- Among 177,618 VLBW infants studied, SIP had a mortality rate of 19%, which was higher than the 5% for those without either condition but significantly lower than the 38% rate for those with NEC.
- The findings emphasize the need to differentiate between SIP and NEC due to their distinct mortality rates, with the greater mortality associated with NEC remaining consistent across all birth weight categories.
Article Synopsis
- Citrulline (CIT) levels were studied in rats after they underwent either proximal or distal small bowel resection to assess the effects on bowel length and nutrition adaptation.
- Both resection groups showed a significant decrease in CIT levels over time compared to sham-operated rats, but there was no notable difference between proximal and distal resection groups.
- The proximal resection group exhibited better intestinal adaptation histologically, as indicated by higher villus height and crypt density, while CIT served as a reliable indicator of intestinal length regardless of the resection site.
Background: Necrotizing enterocolitis (NEC) is a leading cause of death in very low birth weight (VLBW) neonates. The overall mortality of NEC is well documented. However, those requiring surgery appear to have increased mortality compared with those managed medically.
View Article and Find Full Text PDFBackground: Since its introduction as an alternative intestinal lengthening technique, serial transverse enteroplasty (STEP) has been increasingly used as the surgical treatment of choice for patients with refractory short bowel syndrome (SBS). While primary STEP for the treatment of congenital conditions was proposed in the original description of the procedure, emphasis was placed on a delayed or staged approach to these patients. To date, a comprehensive review of the outcomes from this sub-population has not been reported by the International STEP Data Registry.
View Article and Find Full Text PDFPurpose: The serial transverse enteroplasty (STEP) operation tapers and lengthens dilated small bowel. Some patients demonstrate bowel re-dilation following STEP. Factors associated with bowel re-dilation and its effect upon clinical outcome were evaluated.
View Article and Find Full Text PDFBackground: Children with intestinal failure (IF) are at risk for small bowel bacterial overgrowth (SBBO) because of anatomical and other factors. We sought to identify risk factors for SBBO confirmed by quantitative duodenal culture.
Methods: A single-center retrospective record review of children who had undergone endoscopic evaluation for SBBO (defined as bacterial growth in duodenal fluid of >10(5) colony-forming unit per mL) was performed.
Neonatal short bowel syndrome is a disease with a high morbidity and mortality. The management of these patients is complex and requires a multidisciplinary approach. Recent advances in medical and surgical treatment options have improved outcomes.
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