Publications by authors named "Kuan-Cho Chen"
J Med Microbiol
June 2022
Article Synopsis
- Azithromycin (AZM) is an effective treatment for sexually transmitted infections, but resistance to it is increasing globally, especially in Japan.
- A study investigated 93 isolates to understand the relationship between genetic mutations and AZM resistance, particularly focusing on mutations in the 23S rRNA gene and using multi-antigen sequence typing.
- The findings revealed a significant rise in AZM-resistant isolates from 2015 to 2019, highlighting the emergence of specific sequence types (ST4207 and ST6762) associated with higher resistance levels, indicating the need for ongoing monitoring.
