Publications by authors named "Kuan Miao"

Background: The development of machine learning models for aiding in the diagnosis of mental disorder is recognized as a significant breakthrough in the field of psychiatry. However, clinical practice of such models remains a challenge, with poor generalizability being a major limitation.

Methods: Here, we conducted a pre-registered meta-research assessment on neuroimaging-based models in the psychiatric literature, quantitatively examining global and regional sampling issues over recent decades, from a view that has been relatively underexplored.

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Article Synopsis
  • Neuroimaging-based AI diagnostic models have become popular in psychiatry, but their practical use and the quality of reporting on these models are not thoroughly evaluated.
  • The study systematically reviewed the risk of bias and reporting quality of AI models in psychiatry by analyzing 517 studies and using established guidelines for assessment.
  • Findings revealed that a significant majority (83.1%) of AI models had a high risk of bias, with issues such as small sample sizes and poor evaluation of model performance, indicating these models are not yet suitable for clinical practice.
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Preface illustration. The "first-last-author-credit" hierarchy has long been dominated in the scientific incentive system despite intensive calling for contribution-based credits (author contribution statement). In the scientific communities, senior researchers would still make a decision to recommend one's promotion based on first and last positions in authorship rather than their contributions.

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Creativity serves as a fountain for social and scientific development. As one of the most crucial human capabilities, creativity has been believed to be supported by the core component of higher cognitive functions—working memory capacity (WMC). However, the evidence supporting the association between WMC and creativity remains contradictory.

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Negative cognitive processing bias (NCPB) is a cognitive trait that makes individuals more inclined to prioritize negative external stimuli (cues) when processing information. Cognitive biases have long been observed in mood and anxiety disorders, improving validation of tools to measure this phenomenon will aid us to determine whether there is a robust relationship between NCPB and major depressive disorder, anxiety disorders and other clinical disorders. Despite the development of an initial measure of this trait, that is, the negative cognitive processing bias questionnaire (NCPBQ), the lack of psychometric examinations and applications in large-scale samples hinders the determination of its reliability and validity and further limits our understanding of how to measure the NCPB traits of individuals accurately.

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The COVID-19 pandemic prominently hit almost all the aspects of our life, especially in routine education. For public health security, online learning has to be enforced to replace classroom learning. Thus, it is a priority to clarify how these changes impacted students.

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Some plant polysaccharides (PPSs) had been used as the adjuvants for systemic vaccination. In this study, we investigated whether PPSs could exhibit adjuvant effect at the mucosa. Groups of mice were intranasally immunized with Epimedium Polysaccharide (EPS), Trollius chinensis polysaccharide (TCPS), Siberian solomonseal rhizome polysaccharide (SSRPS) and Astragalus polysaccharides (APS) together with ovalbumin (OVA).

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