High and low sodium acetate haemodialysis and ultrafiltration. I. Comparison of haemodynamic effects.

This study was undertaken to evaluate the effect of increasing the dialysate sodium concentration on haemodynamic effects, arterial blood gases and chemistries during haemodialysis and ultrafiltration. Significant changes in mean blood pressure (MBP) and heart rate (HR) were not noted; but significant differences in sodium, potassium, total protein concentration, haematocrit and plasma osmolality during dialysis and ultrafiltration were found with both dialysates. Significant differences were also noted in pCO2 during dialysis and ultrafiltration with both dialysates and increase of pH during dialysis with low sodium dialysate.

Effect of dialysate sodium on the dopamine, adrenaline and noradrenaline concentration in haemodialysis patients.

In eight stable patients, plasma dopamine (DA), adrenaline (A) and noradrenaline (NA) was measured during haemodialysis with high sodium (148mEq/L) and low sodium (131mEq/L) dialysate. During haemodialysis and ultrafiltration with high dialysate sodium an increase of DA, A and NA was not observed in response to the cold pressor test (CD). However, with the low sodium dialysate an increase in DA and NA was observed during CD.

Leukopenia with different regenerated haemodialysis membranes.

The white blood cell count (WBC) decreases during haemodialysis and it was investigated as a function of different dialysis membranes. Each of them was used four times, applying different sterilization methods. Twelve chronic haemodialysis patients were studied and dialysed with cuprophan and polyacrylonitrile (PAN) membranes.

Sympathetic activity, plasma renin activity (PRA) and kininogen levels in patients haemodialysed with acetate and bicarbonate.

Sympathetic, renin and kinin responses to an acetic and bicarbonate fluid in haemodialysed patients were investigated. Increases in dopamine-beta-hydroxylase (DBH) activity, PRA and kininogen levels were found during single dialysis but there was no difference in acetate and bicarbonate haemodialysis. The present results suggest that changes in sympathetic renin and kinin activity were similar in patients treated with either acetate or bicarbonate fluid.

Kinetics of continuous ambulatory peritoneal dialysis (CAPD) with four exchanges per day.

Fourteen patients who had no signs of peritonitis were studied during CAPD. Different exchange time schedules were used alternating exchanges with 1.5% and 2.