Publications by authors named "Kshitij Vashisth"

Alzheimer's disease (AD) is a progressive neurological disorder characterized by memory loss, cognitive decline, and behavioral changes. Immunotherapy aims to harness the immune system to target the underlying pathology of AD and has shown promise as a disease-modifying treatment for AD. By focusing on the underlying disease pathogenesis and encouraging the removal of abnormal protein aggregates in the brain, immunotherapy shows promise as a potential treatment for AD.

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Perception of external cues is important for enhancing the fitness and survival of animals. However, the role of odor perception in regulation of longevity and health is incompletely defined. Here, we show that the exposure to an aversive odor 2-nonanone reduces life span, brood size, feeding rate, and increases lipid storage in worms.

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Article Synopsis
  • * The HSPA1A or Hsp70 protein, which has potential connections to sleep and various health disorders, has been underexplored in research despite its significance.
  • * This paper advocates for investigating Hsp70 as a possible target for new drug development to address sleep disorders and improve outcomes for conditions like cancer and neurodegeneration, emphasizing the need for more research on its molecular mechanisms.
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