Publications by authors named "Ksenia D Golovina"

Article Synopsis
  • - Ischemic stroke is a serious brain disease that triggers complex genetic responses in both sides of the brain after injury, specifically in a rat model.
  • - A study examined RNA sequencing data from two brain hemispheres following ischemia-reperfusion injury, revealing differentially expressed genes (DEGs) that varied in response between the injured and non-injured sides.
  • - The research indicates that understanding these bilateral transcriptome changes could help in developing strategies for brain repair after strokes.
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Ischemic stroke is a multifactorial disease with a complex etiology and global consequences. Model animals are widely used in stroke studies. Various controls, either brain samples from sham-operated (SO) animals or symmetrically located brain samples from the opposite (contralateral) hemisphere (CH), are often used to analyze the processes in the damaged (ipsilateral) hemisphere (IH) after focal stroke.

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