Relationships between Osteopontin, Osteoprotegerin, and Other Extracellular Matrix Proteins in Calcifying Arteries.

Osteopontin (OPN) and osteoprotegerin (OPG) are glycoproteins that participate in the regulation of tissue biomineralization. The aim of the project is to verify the hypothesis that the content of OPN and OPG in the aorta walls increases with the development of atherosclerosis and that these proteins are quantitatively related to the main proteins in the extracellular arteries matrix. Quantitative and qualitative analyses of the OPN and OPG content in 101 aorta sections have been conducted.

3D reconstruction of events: Search for a spatial correlation between injuries and the geometry of the body discovery site.

The aim of the study was to assess the usefulness of analysing visual material in a 3D environment when examining spatial interrelations between the incident participants, tools, and space surrounding the incident site. Such analysis may provide information about the trauma mechanism, which may lead to the determination of probable events. This paper points to the potential of conducting research under 3D environment conditions on the example of a specific criminal incident-a suspected homicide.

Creating crime scene 3D model with body wear camera footage.

Aim: The aim of this study is to develop a methodology for creating 3D images of crime scenes based on footage from cameras used by emergency services. To accomplish this, a research experiment was conducted, which consisted of re-enactment of a crime scene and simulation of the actions of the emergency team. The experiment did not illustrate a real case.

Association between Leukocyte Cell-Derived Chemotaxin 2 and Metabolic and Renal Diseases in a Geriatric Population: A Pilot Study.

LECT2 is not a routine diagnostic marker for any disease, but it has been associated with many pathologies, including systemic amyloidosis, rheumatoid arthritis, diabetes, atherosclerosis, and metabolic syndrome. With human aortic sections ( = 22) and sera from geriatric subjects ( = 79), we analyzed the relationships that could be observed between this protein and other parameters related to metabolic diseases. As a result, we observed a relatively high (r~0.

Relationship between calcification, atherosclerosis and matrix proteins in the human aorta.

Introduction: Extracellular matrix (ECM) proteins have been associated with atherosclerotic complications, such as plaque rupture, calcification and aneurysm. It is not clear what role different types of collagen play in the pathomechanism of atherosclerosis. The aim of the study was to analyze the content of elastin and major types of collagen in the aortic wall and how they associated are with course of atherosclerosis.

Investigations of Human Fascia Lata Elemental Composition-the Effect of Different Preservation and Mineralisation Methods.

Influence of fixation medium and storage conditions as well as impact of sample mineralisation procedure on determination of minerals in human fascia lata was examined and discussed. Freezing and storage in 10% neutral buffered formalin solution and in 2.5% glutaraldehyde were used as the preservation methods of the samples.

The content of collagen type II in human arteries is correlated with the stage of atherosclerosis and calcification foci.

Objective: The signature processes during atherosclerosis development are arterial calcification and accumulation in the arterial walls of proteins that are specific to bone and cartilage, e.g., collagen type II.

Telocytes of Fascial Structures.

Currently, the exact role of telocytes within fascial structures is unknown. The morphology, distribution and behaviour of fascial telocytes as well as the mutual relationship between telocytes and other cellular fascia constituents should be definitely a subject of further studies. It will contribute to better understanding of the role of the fascial system in health and diseases, may shed light on the regeneration potential of these tissues and may help to find targets for future treatments for locomotor disorders, including fascial diseases.

Morphological features of fascia lata in relation to fascia diseases.

Fascia lata is an important element of the fascial system, which forms the continuum of connective tissue throughout the body. This deep fascia envelops the entire thigh and hip area and its main function is to transmit mechanical forces generated by the musculoskeletal system of the lower extremities. Fascia lata is also known as a useful and easily harvested graft material.

Influence of selective digestion of elastin and collagen on mechanical properties of human aortas.

Purpose: There are two families of fibres taking part in the process of mechanical loads transfer, i.e. elastin and collagen fibres.

Electron microscopy of human fascia lata: focus on telocytes.

From the histological point of view, fascia lata is a dense connective tissue. Although extracellular matrix is certainly the most predominant fascia's feature, there are also several cell populations encountered within this structure. The aim of this study was to describe the existence and characteristics of fascia lata cell populations viewed through a transmission electron microscope.

Crime event 3D reconstruction based on incomplete or fragmentary evidence material--case report.

Using our own experience in 3D analysis, the authors will demonstrate the possibilities of 3D crime scene and event reconstruction in cases where originally collected material evidence is largely insufficient. The necessity to repeat forensic evaluation is often down to the emergence of new facts in the course of case proceedings. Even in cases when a crime scene and its surroundings have undergone partial or complete transformation, with regard to elements significant to the course of the case, or when the scene was not satisfactorily secured, it is still possible to reconstruct it in a 3D environment based on the originally-collected, even incomplete, material evidence.

Mineral composition of human fascia lata.

The mineral composition of pathologically unchanged human fascia lata was examined here using inductively coupled plasma optical emission spectrometry (ICP-OES) method for the first time. The total concentrations of Ag, Al, B, Ba, Ca, Cd, Co, Cr, Cu, Fe, Mg, Mn, Mo, Ni, P, Pb, Sr, Ti, V and Zn were simultaneously measured in the tissue secured during autopsy. The age-related changes and between-gender differences in mineral composition of the examined tissue were investigated and discussed.

Chemical composition of human and canine fascia lata.

The fascial system is an integral part of the musculoskeletal system. It is a three-dimensional network of connective tissue spreading ubiquitously throughout the body, surrounding muscles, bones, internal organs, nerves, vessels, and other structures. The basic biophysical properties of the fascial system are determined by its structure and chemical composition.

[Documentation of course and results of crime scene reconstruction and virtual crime scene reconstruction possibility by means of 3D laser scanning technology].

The objective of the study was to present both the possibilities of documenting the course and results of crime scene reconstruction using 3D laser scanning technology and the legal basis for application of this technology in evidence collection. The authors present the advantages of the aforementioned method, such as precision, objectivity, resistance of the measurement parameters to manipulation (comparing to other methods), high imaging resolution, touchless data recording, nondestructive testing, etc. Moreover, trough the analysis of the current legal regulations concerning image recording in criminal proceedings, the authors show 3D laser scanning technology to have a full complete ability to be applied in practice in documentation of the course and results of crime scene reconstruction.

Fatal methanol poisoning complicated with acute coronary syndrome--a case report.

Acute methanol poisoning may cause heart dysfunction accompanied by various electrocardiographic abnormalities. In such cases heart damage is usually secondary to metabolic acidosis and reversible. In this paper the case of fatal methanol poisoning complicated with acute coronary syndrome in a 52-year-old alcohol abuser is presented.

Lethal accidents in storage equipment: a report of two cases.

The paper analyses the causes and mechanisms of death, the possibilities of providing effective emergency assistance, and the regulations for work safety on the basis of two lethal accidents at work in storage equipment. The death mechanism, i.e.

[Suspected azodicarbonamide poisoning in a patient with acute hemorrhaging pancreatitis].

The report describes the case of death of a 22-year old man due to acute hemorrhaging pancreatitis. Azodicarbonamide poisoning was suspected in this patient. Autopsy results, data from the literature and the knowledge about mechanisms of azodicarbonamide toxicity allowed for excluding poisoning with this substance as the cause of death.

Mechanical response of brain to mechanical stimuli--animal model investigation.

Background And Purpose: Conventional neurosurgical procedures give surgeons both tactile and visual feedback. Unlike conventional procedures, minimally invasive surgery is devoid of haptic feedback. Incorporation of tactile feedback into neurosurgical robotic systems can greatly enhance the results of minimally invasive procedures.

[Assessment of the possibilities of application of the thermovision technique in medico-legal diagnosis. Theoretical basis].

The authors in their work wish to prove that technological advancement of modern thermovision technique opens for forensic medicine, as an applied science, new diagnostic possibilities, especially in the scope of the post-mortem examinations. In the past, some attempts were already undertaken to apply thermovision techniques in forensic medicine, those tests, however, were not put in the everyday medical-legal practice. Most of the factors which have an influence in decreasing the value of thermograph tests are not present while biological material is tested post-mortem, therefore, paradoxically, natural elimination of obstacles occurs in such cases, which allows for medical-legal post-mortem diagnostics based on thermograph images.

[The assesment of cranio-cerebral injuries in the aspect of neurological, psychiatric and certification criteria].

In this paper an effort has been made to explain and systemize the notions of encephalopathy, psycho organic syndrome, characteropathy, seen as consequences of cranio-cerebral injuries, and regarding neurological, psychiatric and certificating criteria. The main aim of this classification is to define the necessary conditions needed to confirm or exclude the presence of neurological changes mentioned above. The conditions should be acceptable from the neurological, psychiatric and certificating points of view.

[Clinical and legal aspects for recognizing pneumoconiosis and its outcome, with regard to new imaging techniques].

In this paper different clinical and legal aspects for recognizing anthracosis of the lungs have been presented. Moreover, various methods for indicating or excluding any correlation between this illness and other morbid changes, including those leading to complications, which in turn might cause one's death, have been discussed. Additionally, the usefulness of lung examination by means of high resolution computer tomography (HRCT) in recognizing anthracosis of the lungs has been assessed.

[Regulations for forensic medicine specialists employed as legal experts in Germany and in Poland].

The aim of this paper is to present and compare the regulations for forensic medicine specialists employed as legal experts in Germany and in Poland. The analysis of the legal situation in the two countries and the authors' own experience indicate that there are many similarities as far as the general regulations are concerned. Nevertheless, it seems that forensic medicine specialists employed as legal experts in Germany have more jurisdiction and freedom in their professional activities.