Diagnosis and treatment of pelvic congestion syndrome: Single-centre experiences.

Background: One of the underestimated causes of chronic pelvic pain (CPP) in women may be pelvic congestion syndrome (PCS) that is defined as the presence of varicose of ovarian and pelvic veins associated with chronic pain in the region of the pelvis. This pain is present longer than 6 months and intensifies with prolonged standing, coitus and menstruation. The disease constitutes a diagnostic as well as therapeutic problem, thus posing a challenge for the clinician.

The Formation of Blood Vessel After the Administration of the Plasmid Encoding Ang-1 Gene in Fischer Rats.

Background: Chronic limb ischemia is a serious clinical problem. Patients who do not qualify for standard treatment may benefit from novel gene therapies.

Objectives: This study evaluated angiogenesis following intramuscular injections of angiogenic plasmid Ang-1 in Fisher rats.

Surgical management of extracranial carotid artery aneurysms.

Background: We present the methods and results of the surgical management of extracranial carotid artery aneurysms (ECCA). Postoperative complications including early and late neurological events were analysed. Correlation between reconstruction techniques and morphology of ECCA was assessed in this retrospective study.

Type of Renal Replacement Therapy (Hemodialysis versus Peritoneal Dialysis) Does Not Affect Cytokine Gene Expression or Clinical Parameters of Renal Transplant Candidates.

Unlabelled: Patients with renal failure suffer from immune disturbances, caused by uremic toxins and influenced by dialysis treatment. The aim of the present study was to reveal whether type of dialysis modality (hemodialysis, HD, versus peritoneal dialysis, PD) differentially affects the immunocompetence, particularly the expression of genes involved in the immune response.

Material: 87 renal transplant candidates (66 HD, 21 PD) were included in the study.

Combined autologous bone marrow mononuclear cell and gene therapy as the last resort for patients with critical limb ischemia.

Introduction: Our study was designed to investigate the safety and efficacy of combined autologous bone marrow mononuclear cell (MNC) and gene therapy in comparison to conventional drug therapy in patients with critical limb ischemia (CLI).

Material And Methods: Thirty-two patients with CLI persisting for 12-48 months (average time 27.5 months) were randomized into 2 groups, each group consisting of 16 patients.

Serum and urine metabolomic fingerprinting in diagnostics of inflammatory bowel diseases.

Aim: To evaluate the utility of serum and urine metabolomic analysis in diagnosing and monitoring of inflammatory bowel diseases (IBD).

Methods: Serum and urine samples were collected from 24 patients with ulcerative colitis (UC), 19 patients with the Crohn's disease (CD) and 17 healthy controls. The activity of UC was assessed with the Simple Clinical Colitis Activity Index, while the activity of CD was determined using the Harvey-Bradshaw Index.

[Stem and progenitor cells in biostructure of blood vessel walls].

Development of vascular and hematopoietic systems during organogenesis occurs at the same time. During vasculogenesis, a small part of cells does not undergo complete differentiation but stays on this level, "anchored" in tissue structures described as stem cell niches. The presence of blood vessels within tissue stem cell niches is typical and led to identification of niches and ensures that they are functioning.

Transplantation of autologous bone marrow mononuclear cells with VEGF gene improves diabetic critical limb ischaemia.

Introduction: The aim of this study was to assess the safety and efficacy of combined autologous bone marrow mononuclear cell and VEGF165 gene therapy in patients with diabetes mellitus suffering from critical limb ischaemia (CLI).

Material And Methods: The administration of mononuclear cells (MNCs) and naked VEGF165 plasmid was performed in 16 limbs of 16 patients with rest pain and ischaemic ulcers due to diabetes. MNCs and plasmid were injected into the muscles of the ischaemic limbs.

[Usage of hydrophilic catheters and guidewires in endovascular surgery].

Aim Of Study: The aim of this study was to evaluate the effectiveness of hydrophilic catheters and guidewires during endovascular overcoming long stenoses or occlusions of the superficial femoral and popliteal artery.

Material And Methods: Based on 142 procedures rated the functionality of the equipment of the hydrophilic coating. The operations were performed in the years 2010-2012 in the Department of Vascular, General and Transplantation, Medical University in Wroclaw.

Evaluation of the humoral and cellular immune responses after implantation of a PTFE vascular prosthesis.

Introduction: The experiment was designed in order to determine the immunological processes that occur during the healing in synthetic vascular grafts, especially to establish the differences in the location of the complement system proteins between the proximal and distal anastomosis and the differences in the arrangement of inflammatory cells in those anastomoses. The understanding of those processes will provide a true basis for determining risk factors for complications after arterial repair procedures.

Material/methods: The experiment was carried out on 16 dogs that underwent implantation of unilateral aorto-femoral bypass with expanded polytetrafluoroethylene (ePTFE).

[The treatment of dissected thoraco-abdominal aorta aneurysm with the use hybrid procedure].

Aim Of Study: We analyzed the case of a patient treated in Vascular Surgery Department with the use of the hybrid procedure with a good results.

Materials And Methods: Acute cases of dissected aortic aneurysm are commonly known as an immediate danger of human live and determinate a big challenge for physicians. The collaboration of classic and endovascular methods (hybrid procedures) gives much more chances to improve patient's survival and resumption to normal life activity.

[The surgical treatment of thoracic outlet syndrome].

Unlabelled: In this paper the surgical treatment of thoracic outlet syndrome (TOS) is presented.

Material And Methods: The investigation of 74 patients treated for vascular complications of the TOS the Paget-Schroetter syndrome and postthrombotic syndrome (27 patients), as well as upper limb ischemia and/or the subclavian artery aneurysm (14 patients) and for neurological complications of the TOS (33 patients) was performed. In case of venous thrombosis the treatment consisted of thrombolytic therapy and decompressive procedures that included transaxillary first rib resection and other surgical procedures that excise different anomalies in the region of the thoracic outlet.

[Incidence of factor VII and C3 in vascular anastomosis].

In order to study pathogenesis of vascular prosthesis healing process the following experiment was designed. 16 dogs underwent implantation of unilateral straight aorto-femoral teflon (PTFE, polytetrafluoroethylene) by-pass. After 6 months all dogs were killed, dissected and vascular prostheses with margin of adjacent aorta and femoral artery were collected for further study.

[Presence of Chlamydia pneumoniae in the carotid artery].

Unlabelled: There is growing experimental evidence that Chlamydia pneumoniae is a risk factor and contribute to the development of atherosclerosis of carotid artery. This process might cause stenosis of carotid artery and TIA or stroke.

Aim: Aim of this study was to evaluate the frequency of Ch.

[Immunosuppression in the treatment of vascular prosthesis infection with arterial transplantation].

Aim: The purpose of this study is to evaluate the use of immunosuppression in treatment of prosthetic graft infections with arterial transplantation.

Material And Methods: In this paper 29 cases of the massive aorto-ilio-femoral graft infection treated by the replacement of infected prosthesis with arterial homograft are presented. The arterial allograft was stored with application of cold ischemia method in preservation solution at 4 degrees C.

Treatment of a rare case of local prosthetic graft infection with silver coated prosthesis.

The infection after synthetic vascular prosthetic graft implantation remains a serious complication of reconstructive vascular surgery. Surgical treatment consists of complete removal of the infected vascular graft with the preservation of the limb circulation. In this paper the case of aortofemoral by-pass infection limited to the distal part of the branches is presented.

The treatment of massive prosthetic grafts infections with the use of silver/collagen coated dacron vascular prosthesis.

In this paper the use of silver-coated medical prosthesis of massive aorto-bifemoral and ilio-femoral dacron graft infection with hemorrhage is presented. To solve this problem in situ replacement was attempted using silver-coated dacron vascular prosthesis more resistant to infection. 9 patients with this therapeutic method is reported.