Effect of mucoprotective plant-derived therapies on damage to colonic mucosa caused by carprofen and robenacoxib administered to healthy dogs for 21 days.

Background: Non-steroidal anti-inflammatory drugs (NSAIDs) may cause gastrointestinal damage in dogs.

Hypothesis/objectives: To determine the extent to which lansoprazole, liquorice extract, and a herbal solution exhibit protective effects on colonic mucosa when administered to dogs concurrently with the NSAIDs carprofen or robenacoxib.

Animals And Methods: Thirty-five healthy beagle dogs (15 male and 20 female) aged 13-14 weeks and weighing 4.