Nanoskin® to treat full thickness skin wounds.

This experimental study evaluated 40 guinea pigs that received Nanoskin®. A full thickness skin rectangle measuring 2x4 cm was removed from the median dorsal region and the wound was covered by a 2X2 cm fragment of uncoated Nanoskin® graft (uncoated group) or Nanoskin® coated with gelatin (coated group) and sutured in the caudal region and a 2x2 cm fragment of autologous skin sutured in the cranial aspect of the surgical wound served a control. The animals were examined daily by ectoscopy and euthanized at 7, 30, 90 and 180 days postoperatively.