Expanding the Availability of Scalp Cooling to All Patients at Risk of Chemotherapy-Induced Alopecia.

Alopecia is an undesirable side effect of cancer chemotherapy. The mitigation of alopecia is a desirable adjunct treatment for patients with cancer. FDA-cleared scalp cooling (SC) devices have been successfully used to prevent or reduce chemotherapy-induced alopecia (CIA).

Effect of emollients on UV filter absorbance and sunscreen efficiency.

The idea of increasing the performance of sunscreens without adding more UV-filters is very attractive. Early studies reported an influence of solvents on the absorbing properties of UV-absorbers which was shown to be connected to the solvent polarity. However, the polarity differed a lot between tested solvents and most were unsuitable UV-filter solubilizers.

Liquid-crystalline membrane permeation ability for selected nitro hair dyes.

Aim: A comparison of permeation ability of selected semi-permanent hair dyes and an attempt to estimate the influence of fundamental physicochemical parameters on dyes' epidermal penetration rate.

Methods: Dyes' permeation ability through liposome membrane (as a model of stratum corneum) with side-by-side cells was assessed.

Results: It has been shown that the chosen dyes are capable of permeating the membrane.

[Pulmonary microscopic lesions in drug addicts--a preliminary report].

Background: A sudden death of drug addicts is generally attributed to the depressive effect of substances in question on the respiratory center in the CNS. Microscopic morphology of lungs is relatively rarely dealt with.

Purpose: This study probes into the morphology of individuals who were intoxicated by amphetamine and/or heroin and suddenly died.

Comparative morphology of the hepatic and coronary artery walls. Part III. The insignificance of medial morphologic features in the determination of an autopsied unidentified subjects age.

Since hepatic arteries are free of atherosclerosis any possible wall structure change may be attributed to age. We determined the media of hepatic and coronary arteries in view of this assumption. We measured its thickness and myocytic density (per 1 mm2 of cross-section) from specimens collected from autopsied subjects, aged up to 90 years.

Comparative morphology of the hepatic and coronary artery walls. Part II. The relation between the internal elastic membrane, non-atherosclerotic intimal thickening and atherosclerosis.

Evident difference in the occurrence of atherosclerosis between hepatic and coronary arteries justifies the search for local preconditions of this disease. In this study we compared the internal elastic membrane morphology of both arteries. It appeared to be mono- or polylinear (laminar) and continuous in the hepatic artery.

Comparative morphology of the hepatic and coronary artery walls. Part I. Differences in the distribution and intensity of non-atherosclerotic intimal thickening and atherosclerosis.

We compared the morphology of the hepatic artery intima which is free of atherosclerosis, with that of the typically atherosclerosis-prone coronary artery. The study group comprised material collected from 116 autopsies. Subjects were aged between 1 month and 90 years.

Light and electron microscopic picture of atherosclerotic plaque in stable and unstable angina.

By presenting this series of 127 cases of coronary atherectomy the authors join the workers who study morphological differences between the atherosclerotic plaques in stable and unstable angina. Routine staining of formalin-fixed, paraffin-embedded material was completed by the detection of T lymphocytes, macrophages, mast cells, smooth myocytes and grown-in capillaries using monoclonal antibodies (DAKO), as well as by the immunofluorescent demonstration of fibrinogen in the plaques. The plaques derived from patients with unstable angina showed a higher incidence of mast cells (significant) and macrophages (insignificant).

Restoration of the continuity of dog ureter after resection of its 5 cm middle segment.

Objective: To evaluate the restoration of the ureter of the dog after resection of a 5 cm-long middle segment.

Materials And Methods: Eight dogs underwent resection of the middle segment of the ureter, after which a 6-8 F Bard ureteric stent modelling catheter was inserted into both remaining portions of the ureter for 3 months. One month after removal of the stent the animals were killed and their ureters examined both grossly and microscopically.

[Correlation among clinical and histopathologic criteria in selection of donors for orthotopic liver transplantation].

The aim of this work is to present the correlation between the initial microscopic pattern of the liver graft and clinical and laboratory findings. In the Department of General Surgery and Liver Diseases 6 specimens were taken from 4 livers destined for planned liver transplantations. They were taken from the organ rinsed in UW solution, processed and stained extemporaneously.

[Giant cell arteritis--presentation of 3 cases].

Three patients with giant cell arteritis (GCA) observed recently in our department are described. One of them demonstrated clinical picture of polymyalgia rheumatica, the other two presented with clinical symptoms of GCA. This presentation seems to be very helpful for correct diagnosis in cases with difficult recognition.

[A case of Whipple's disease].

We present 66 year old man with symptoms of malabsorption syndrome. The correct diagnosis of Whipple's disease was made difficult by the radiological picture of the jejunum tumor with subocclusion. It was the cause of the diagnosis of carcinoid tumor of the small intestine: the laparotomy was performed.

[Ruptured aneurysm of the abdominal aorta into the duodenum as a cause of hemorrhage from the digestive tract].

An extremely rare cause of bleeding from the digestive tract is presented which was a rupture of abdominal aorta aneurysm into duodenal lumen. On the basis of history data, clinical picture and gastroscopy, bleeding from gastric ulcer was diagnosed. The actual cause of bleeding was established during autopsy, not confirming at the same time the presence of gastric ulcer.

[Anatomic study of the direct vascular connection between the adrenal gland and kidney in humans].

The study was performed on 16 specimens containing adrenal gland and kidney obtained at route autopsy. The mixture of gelatin and india ink was injected into adrenal artery, through the catheter. In all specimens vessels leaving adrenal gland and entering cortex of kidney were found.

[Renal biopsy in the aged].

Pathological findings in urinalysis in the aged persons are usually thought to be caused by pathologic processes other than glomerulopathy. Histological evaluation of renal tissue in older patients is extremely difficult due to coexistence of involuntary changes-hyalinosis, increase in mesangial matrix content, and vascular changes. The aim of the study was to evaluate frequency of glomerulonephritis, both primary and secondary in persons older than 60.

Relation between cardiovascular pathologic conditions and malignant tumours as seen by pathologist. II. Myocardial infarct and coronary atherosclerosis in the population suffering from malignant neoplasm as seen by pathologist.

In the autopsy material of 2932 men and 3051 women the frequency of fresh myocardial infarct and the severity of coronary atherosclerosis were highly significantly lower in the population suffering from malignancies than in that free of cancer. Lower frequency of myocardial infarct seems to result from lower severity of coronary atherosclerosis. The incidence rate of myocardial infarct was also significantly lower in the cancer--bearing group when both compared populations showed identical, severe (grade 4) coronary atherosclerosis.

Relation between cardiovascular pathologic conditions and malignant tumours as seen by pathologist. I. Frequency of malignant neoplasms in the population with myocardial hypertrophy as seen by pathologist.

Relatively low co-existence of malignant neoplasms and chronic cardiovascular disease was documented in this work the emphasis being put on the conditions running with myocardial hypertrophy. The percentage of malignancy in the total autopsy material of 5821 men and 6849 women was 27.8 and 23.