[Evaluation of the effectiveness of the drug Cytoflavin in patients with dyscirculatory encephalopathy who have undergone a new coronavirus infection].

Objective: To evaluate the effectiveness of the Cytoflavin in patients with dyscirculatory encephalopathy (DE) who had a new coronavirus infection.

Material And Methods: 82 patients were examined: 16 (19.5%) men and 66 (80.

[BIOLOGICAL TREATMENT OF PSORIASIS IN TIME OF NEW CORONAVIRUS INFECTION COVID-19].

Currently, the ongoing pandemic of the novel coronavirus infection is still a major public health problem worldwide. The questions of immunosuppressive therapy of patients with psoriasis and psoriatic arthritis, the possibility of vaccination against the background of the use of genetically engineered drugs remain open. The article is of an overview nature and includes up-to-date information on the feasibility and safety of the use of genetically engineered biological drugs in patients with psoriasis in a pandemic (COVID-19).

[Combined action of low-intensity laser radiation and autologous plasma with blood cells on the microcirculatory apparatus of the skin during involution changes.].

Involutional changes of the skin are associated with changes in its microcirculatory apparatus, among which spastic, atonic and mixed types are distinguished. The effect of low-intensity laser radiation in combination with autologous plasma with blood cells on the vascular component of the skin was studied. In the light of the restoration of the microcirculatory apparatus of the skin in different types, the clinical efficacy of the therapy was analyzed.

Treatment of Moderate to Severe Acne and Scars With a 650-Microsecond 1064-nm Laser and Isotretinoin.

Background: Laser procedures for acne and acne scars have traditionally been postponed for at least 6 to 8 months after the end of systemic isotretinoin therapy. Lower dosages with more modern laser devices having unique energy parameters of high power in microsecond pulse durations have made it possible to administer laser therapy during or shortly after completion of isotretinoin therapy, thus reducing the risk of side effects of isotretinoin.

Methods: Patients with moderate to severe facial acne (n=46) and atrophic scars enrolled in a 6-month study.

First Measurement of a Long-Lived π^{+}π^{-} Atom Lifetime.

The adapted DIRAC experiment at the CERN PS accelerator observed for the first time long-lived hydrogenlike π^{+}π^{-} atoms, produced by protons hitting a beryllium target. A part of these atoms crossed the gap of 96 mm between the target and a 2.1  μm thick platinum foil, in which most of them dissociated.

[Mental disorders, social maladaptation and quality of life of patients with acne and post-acne symptoms].

Aim: A comparative analysis of the psycho-emotional status and quality of life of patients with acne and post-acne.

Material And Methods: There were 147 patients included in the study, 84 (57%) women and 63 (43%) men, aged from 14 to 48 years. The following parameters were studied: CADI score, APSEA score, DLQI score.

Observation of π^{-}K^{+} and π^{+}K^{-} Atoms.

The observation of hydrogenlike πK atoms, consisting of π^{-}K^{+} or π^{+}K^{-} mesons, is presented. The atoms are produced by 24  GeV/c protons from the CERN PS accelerator, interacting with platinum or nickel foil targets. The breakup (ionization) of πK atoms in the same targets yields characteristic πK pairs, called "atomic pairs," with small relative momenta Q in the pair center-of-mass system.

[Approaches to phototherapy in children with chronic dermatosis (review of literature)].

The article covers main aspects of phototherapy and photochemotherapy in treatment of skin diseases in children, risks of such methods usage, prophylactic and therapeutic measures, and precaution means for such treatment in pediatrics.

[Combined treatment of palmoplantar syndrome in patients under antitumor therapy].

Observation covered 12 patients under various antitumor medications. Group 1 was formed of patients with developed palmoplantar syndrome varying in severity, who received complex treatment including IR-therapy and local antioxidant medication. Group 2 included patients without palmoplantar syndrome, who received preventive treatment with IR-therapy.

Prophylaxis and rehabilitation of patients with chronic dermatosis (review of literature).

The article covers main aspects of sanatorium-and-spa treatment in chronic skin diseases.

Physical therapy methods for treatment and rehabilitation of oncologic patients (review of literature).

Oncologic morbidity has a tendency to steady rise. Treatment of oncologic patients, aimed to remove or cease malignant cells growth and prevent metastases, has considerable side effects and is conducted on psychologic stress background. Rehabilitation measures hence get crucial importance.

Recovery treatment of lower limbs trophic ulcers in patients with chronic venous insufficiency (review of literature).

Trophic ulcers are complications of chronic venous insufficiency in 15-18% of cases and appear in 1-2% of able- bodied population. The frequency increases with age up to 4-5% among the patients aged over 65, and radical removalof the disease can be achieved only in one tenth of the patients. With that, even healed trophic ulcers recur frequently: after surgery in 4,8-31,6% of cases (according to various authors), after conservative treatment in 15-100% of cases.

[Variations of HBD-2 and TLR-2 gene expression in patients presenting with lichen ruber planus under effect of ultraviolet irradiation].

The combination of narrow-band range UV-A (311 nm) and middle/broad-band UV-B (320-400 nm) irradiation was shown to significantly reduce manifestations of objective and subjective symptoms in the patients presenting with lichen ruber planus. Moreover, it promoted elimination ofdisbalance between characteristics of congenital immunity and normalization of HBD-2 and TLR-2 gene expression.

[Growth factors are markers of placental insufficiency in third-trimester miscarriage].

The paper characterizes placental growth factors in the third trimester of pregnancy. The placental expression of vascular endothelial growth factor (VEGF) and transforming growth factor-beta2 (TGFbeta2) was studied in miscarriage after 34-37 weeks pregnancy and during term labor. Chronic placental insufficiency was diagnosed in miscarriage.

[The nature of the action of chemical substances on the activity of the microflora in soft dental deposits].

Effects of the principal mineral and mineralizing components of the saliva, nutrient organic acids (carbohydrate and some others substances' metabolites) on the activity of microflora of soft dental deposit were studied in vitro. The inhibitory effect was assessed visually from the appearance or absence of deposit coating, pH measurement, and by photo- and nephelometry. Concentrations of lactic acid and sucrose were measured.

[The nature of the distribution and utilization of saccharose in the oral cavity after carbohydrate loading].

Sucrose content on surface of oral tissues and in the oral fluid following a carbohydrate loading was studied in vivo synchronously and over time. The content of sucrose adsorbed by oral tissues was assessed by its desorption with applications. Sucrose concentrations were the highest in the liquid closest to tissues in comparison with its levels in the saliva in general, this indicating a high cariogenic potential of the buccal mucosa due to intake of easily fermented carbohydrates.

[The nature of the primary interaction of saccharose from aqueous solutions with the oral cavity tissues].

The course of saccharose adsorption on surface tissues of the oral cavity directly after carbohydrate loading was studied in vivo. The amount of saccharose adsorbed on tissue surface was assessed from its desorption from an isolated site of the solid phase of the oral cavity and was correlated to a unit of tissue surface. Cariogenic potential in the oral cavity was shown to be maintained to a great measure at the expense of soft tissues and, specifically, of the glossal mucosa which is characterized by a high adsorption capacity for saccharose and represents a sort of a saccharose "depot" in the oral cavity.

[The effect of mineral and organic substances on the desorption of sugar from a soft dental deposit].

Effects of the principle mineral and mineralizing components of the saliva, alimentary organic acids-products of carbohydrate metabolism, and of some other substances of various pH on sugar desorption from soft dental deposit were compared in vitro. The desorbing efficacy was assessed from the concentration of sucrose, derived from a sample of lyophilized dental deposit, in a suspension of the tested reagent. The major mineral components of the saliva, calcium and phosphate, were found to promote extraction of sucrose from the deposit in neutral and weakly alkaline media.

[State of pulmonary surfactant in different species of animals].

The authors have shown that pulmonary surfactand activity in mice, rats, guinea pigs, hamsters, rabbits and dogs was within the normal limits with the fluctation of the air vesicle stability coefficient of from 0.84 to 0.93.