Publications by authors named "Krittiya Thisayakorn"
Unlabelled: Gamma oryzanol (GO) is the rice bioactive compound which presents various therapeutic effects. However, GO is relatively unstable to environmental factors during processing and storage. The objective of this work was to produce GO microparticles encapsulated with inulin and Tween80 (GOINs) by spray-drying.
View Article and Find Full Text PDFEthnopharmacological Relevance: Sa-Tri-Lhung-Klod (ST) remedy is a Thai traditional remedy used in obstetrics and gynecology to reduce inflammation and nourish the body post-partum. In Thai traditional medicine (TTM), there is a theory of formulating drugs based on the four elements and the tastes of herbs for use in treating diseases.
Aims Of Study: To determine relationships between taste theory and pharmacological properties for the anti-inflammatory effect of ST remedy and its chemical constituent components.
Article Synopsis
- The Kheaw-Hom (KH) remedy, a traditional Thai medicine known for treating fever and inflammation in children, has not previously been studied for its anti-inflammatory effects or bioactive compounds.
- This study aimed to assess the in vitro and in vivo anti-inflammatory properties of KH remedy and its key compound, ethyl p-methoxycinnamate (EPMC), while investigating the connection between flavor and ethnopharmacological functions based on traditional Thai medicine theory.
- Results revealed that a specific preparation of KH (KHP-h) exhibited the highest EPMC content and effectively reduced inflammatory markers in both cell cultures and in vivo experiments, indicating its potential as a therapeutic anti-inflammatory agent.
Article Synopsis
- The Prasachandaeng (PSD) remedy, used in Thailand for centuries to reduce fever, was found to have significant antipyretic effects similar to acetaminophen (ACP) in a study involving rats.
- When examining liver safety, various PSD forms showed no signs of damage, with liver function tests indicating normal levels and less hepatotoxicity compared to ACP.
- Histopathological analysis confirmed these findings, demonstrating that both PSD powder and ethanol extract were effective at lowering fever without harmful effects on liver health over a seven-day period.
Intracellular amyloid-β (Aβ) oligomers are key therapeutic targets because they are strongly cytotoxic and play crucial roles in the cognitive function in Alzheimer's disease (AD). Anthocyanins, polyphenolic flavonoids with antioxidant and neuroprotective properties, are potential therapeutic candidates for AD. Here, we investigated the effects of anthocyanin-enriched extracts from fruits of mulberry (Morus alba Linn.
View Article and Find Full Text PDFGamma oryzanol (GO), a bioactive ingredient found in rice bran oil, performs a variety of biological effects such as antioxidant activity, reduction of total cholesterol, anti-inflammation, and antidiabetes. However, GO is water-insoluble and normally degrades through oxidation. Thus a nano-encapsulation technique was investigated to improve its stability and quality.
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