Publications by authors named "Krithika Gopalakrishnan"
Article Synopsis
- Varicella zoster virus (VZV) can lead to serious neurological conditions, either as complications during initial infection or when the virus reactivates, with better outcomes if diagnosed early and treated with antiviral drugs.
- In a study involving 30 unvaccinated participants, VZV DNA was found in one case while anti-VZV IgG was present in a significant majority, highlighting varied clinical presentations such as meningitis and altered sensorium.
- Routine testing for both VZV DNA and anti-VZV IgG in cerebrospinal fluid (CSF) is essential to improve early detection and reduce complications from VZV reactivation.
Rotaviruses by virtue of its segmented genome generate numerous genotypes. G1P[8] is the most common genotype reported globally. We intend to identify the evolutionary differences among G1P[8] strains from the study with vaccine strains.
View Article and Find Full Text PDFBackground: Neonatal rotavirus infections are predominantly caused by distinct genotypes restricted to this age-group and are mostly asymptomatic.
Method: Stool samples from neonates admitted for >48 h in neonatal intensive care units (NICUs) in Vellore (2014-2015) and Chennai (2015-2016) in southern India, and from neonates born at hospitals in Vellore but not admitted to NICUs (2015-2016) were tested for rotavirus by ELISA and genotyped by hemi-nested RT-PCR.
Results: Of 791 neonates, 150 and 336 were recruited from Vellore and Chennai NICUs, and 305 were born in five hospitals in Vellore.