Publications by authors named "Krisztina Dorizas"
Erratum for Drusano et al., "Dilution Factor of Quantitative Bacterial Cultures Obtained by Bronchoalveolar Lavage in Patients with Ventilator-Associated Bacterial Pneumonia".
George L Drusano Michael L Corrado Gino Girardi Evelyn J Ellis-Grosse Richard G Wunderink Krisztina Dorizas
Antimicrob Agents Chemother
April 2018
Article Synopsis
- Ventilator-associated bacterial pneumonia (VABP) presents a challenging treatment dilemma, with ongoing debates about the best antibiotic approach and recent guidelines recommending a 7-day course due to benefits like reduced mortality and resistance.
- The study focuses on measuring the bacterial load in patients suspected of having VABP by analyzing bronchoalveolar lavage (BAL) fluid and calculating a dilution factor to estimate the true bacterial burden.
- Findings reveal a median dilution factor of 28.7, indicating significant bacterial counts that could influence treatment efficacy, particularly as high bacterial loads can hinder the effectiveness of the immune response.