Robotic pelvic side-wall lymph node dissection for rectal cancer: a systematic review of videos and application of the IDEAL 2A framework.

Lateral pelvic lymph node dissection (LPLND) in rectal cancer has gained increasing traction worldwide. Robotic LPLND is an emerging technique. Utilising the IDEAL (idea, development, exploration, assessment and long-term follow-up) framework for surgical innovation, robotic LPLND is currently at the IDEAL 2A stage (development) mainly limited to case reports, case series and videos.

A pioneer Australian case of Savi-Scout™ assisted resection for breast cancer recurrence.

This case describes a 48-year-old female who the first patient in Australia treated surgically with Savi-Scout™ assisted breast cancer localization, utilizing electromagnetic wave signalling for accurate depth guidance. After initial breast cancer diagnosis at age 44 treated with bilateral mastectomies and DIEP flap reconstructions, clinical surveillance found recurrent right chest wall disease. US and MRI identified a 4-6 mm interpectoral lesion; poorly differentiated metastatic micropapillary carcinoma on core biopsy.

Advances in our understanding of the pathophysiology of Type 1 diabetes: lessons from the NOD mouse.

T1D (Type 1 diabetes) is an autoimmune disease caused by the immune-mediated destruction of pancreatic β-cells. Studies in T1D patients have been limited by the availability of pancreatic samples, a protracted pre-diabetic phase and limitations in markers that reflect β-cell mass and function. The NOD (non-obese diabetic) mouse is currently the best available animal model of T1D, since it develops disease spontaneously and shares many genetic and immunopathogenic features with human T1D.