Publications by authors named "Kristoffer Juul Nielsen"
Background: Oral squamous cell carcinoma (OSCC) is responsible for high morbidity and mortality worldwide. Although the oral cavity encompasses different anatomical subsites, it is unclear whether subsite localization of carcinoma influences outcome.
Methods: This retrospective cohort study examined overall survival (OS), recurrence-free survival (RFS) and local recurrence-free survival (L-RFS) at different subsites by Kaplan-Meier survival curves.
Article Synopsis
- The study evaluates how smoking status, tobacco exposure, and quitting smoking influence overall and disease-free survival rates in patients with oral squamous cell carcinoma (OSCC).
- A total of 1717 patients from Copenhagen were analyzed, revealing that current smokers have lower survival rates compared to never-smokers, while former smokers show better outcomes.
- Results indicated that both accumulated tobacco exposure and ongoing smoking after diagnosis negatively impacted long-term survival, emphasizing the importance of smoking cessation for improving patient prognosis.
Objectives: Nasopharyngeal malignancies are reported having decreasing incidence and reduced mortality. This study provides a nationwide update of the incidence and survival in Denmark.
Materials And Methods: The Danish Cancer Registry (DCR) and Central Population Register (CPR) were used to identify all patients registered with nasopharyngeal malignancies between 1980 and 2014 in Denmark.
Human papillomavirus (HPV) imposes an increased risk of developing cervical, anal and oropharyngeal cancer. In the Western world, HPV infection is currently the major cause of oropharyngeal cancer. The effectiveness of HPV vaccines for oral or oropharyngeal HPV infection is yet to be determined.
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