Publications by authors named "Kristine Walters"

Objective: To report a novel presentation of feline hemangiosarcoma.

Animals: A 14-year-old spayed female feline patient diagnosed with hemangiosarcoma of the spleen and a cervical lymph node.

Clinical Presentation, Progression, And Procedures: The patient presented to the emergency service following a 1-week history of lethargy and hiding.

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Background: Both human and veterinary cancer chemotherapy are undergoing a paradigm shift from a "one size fits all" approach to more personalized, patient-oriented treatment strategies. Personalized chemotherapy is dependent on the identification and validation of biomarkers that can predict treatment outcome and/or risk of toxicity. Many cytotoxic chemotherapy agents, including doxorubicin, base their mechanism of action by interaction with DNA and disruption of normal cellular processes.

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