Publications by authors named "Kristine W A C Koekkoek"

Article Synopsis
  • Micronutrient (MN) alterations in critically ill patients can lead to complications, but improving MN status may help as a supportive therapy.
  • This review, done by a specialized group, focuses on individual important MNs, such as vitamins A, B, C, D, E, as well as minerals like iron and zinc, to guide future research.
  • It emphasizes that high-dose single MN treatments are not advised; instead, patients should receive daily basal needs, with adjustments for higher requirements and treatment for deficiencies, and lists ongoing trials and future research priorities.
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In the Emergency Department (ED) actual body weight (ABW) is essential for accurate drug dosing. Frequently, the ABW is unknown and direct measurement troublesome. A method using the mid-arm circumference (MAC) to estimate ABW has been developed and validated in the United States of America (USA).

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Purpose Of Review: To provide an overview of recent findings concerning refeeding syndrome (RFS) among critically ill patients and recommendations for daily practice.

Recent Findings: Recent literature shows that RFS is common among critically ill ventilated patients. Usual risk factors for non-ICU patients addressed on ICU admission do not identify patients developing RFS.

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Background: Adequate nutrition is essential during critical illness. However, providing adequate nutrition is often hindered by gastro-intestinal complications, including feeding intolerance. It is suggested that hyperosmolar medications could be causally involved in the development of gastro-intestinal complications.

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Purpose Of Review: The narrative review aims to summarize the relevant studies from the last 2 years and provide contextual information to understand findings.

Recent Findings: Recent ICU studies have provided insight in the pathophysiology and time course of catabolism, anabolic resistance, and metabolic and endocrine derangements interacting with the provision of calories and proteins.Early provision of high protein intake and caloric overfeeding may confer harm.

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Purpose Of Review: To summarize recent relevant studies regarding nutrition during critical illness and provide recommendations for clinical practice.

Recent Findings: Recently acquired knowledge regarding nutritional status and risk assessment, body composition, gastric residual volume, prokinetics, tube positioning, enteral vs parenteral nutrition, nutritional dose and timing of initiation, pharmaconutrition, dysbiosis and probiotics are discussed.

Summary: Body composition especially lean body mass is associated with clinical outcomes.

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