Publications by authors named "Kristine Schmalenberg"

Article Synopsis
  • - This study evaluated the effectiveness and tolerability of a topical serum against a single ablative laser treatment over 16 weeks for women with signs of photodamage on their faces.
  • - Results showed that the topical serum led to significantly better improvements in various skin conditions, such as fine lines and wrinkles, compared to the laser treatment.
  • - Both treatments had similar tolerability, but the topical serum resulted in better or equivalent improvements in skin appearance after the 16-week period.
View Article and Find Full Text PDF

This paper describes the synthesis and cytotoxicity of poly(anhydride esters) that are composed of several salicylate derivatives, including halogenated salicylates, aminosalicylates, salicylsalicylic acid, and thiolsalicylic acid. The incorporation of these nonsteroidal antiinflammatory drugs (NSAIDs) into a biodegradable polymer backbone yields drug-based polymers that have potential for a variety of applications. The poly(anhydride esters) were synthesized by melt condensation polymerization.

View Article and Find Full Text PDF

Microcontact printed polymeric substrates were evaluated for their ability to control Schwann cell attachment and direct proliferation, as Schwann cell guidance is a crucial factor in directing peripheral nerve regeneration. Elastomeric stamps of poly(dimethylsiloxane) were "inked" with laminin, a permissive protein for Schwann cell adhesion, and stamped onto poly(methyl methacrylate) substrates to create patterns of lines and intervals varying from 10 to 50 microm wide. Schwann cells were seeded onto the substrates in serum-free media.

View Article and Find Full Text PDF