Motility patterns of ex vivo intestine segments depend on perfusion mode.

Aim: To evaluate and characterize motility patterns from small intestinal gut segments depending on different perfusion media and pressures.

Methods: Experiments were carried out in a custom designed perfusion chamber system to validate and standardise the perfusion technique used. The perfusion chamber was built with a transparent front wall allowing for optical motility recordings and a custom made fastener to hold the intestinal segments.