Electronic survey investigating UK veterinarians' perceptions of the potential for veterinary prescription medication misuse or abuse.

Objective: To investigate veterinarians' experience and perception of the risk of veterinary prescription medication (VPM) misuse and abuse by the public and veterinary professionals and to determine the clinical context in which respondent veterinarians prescribed certain VPMs.

Study Design: Anonymous online voluntary survey.

Population: A total of 361 of 7126 veterinarians registered as practicing in the UK, who provided e-mail contact details to the Royal College of Veterinary Surgeons Knowledge for participation in research.

Evaluation of two different radiotherapy anaesthetic protocols for dogs: a randomized clinical crossover trial.

Objectives: To describe alfentanil-propofol admixture for induction of anaesthesia for canine radiotherapy and compare it to alfentanil-atropine followed by propofol induction in terms of heart rate (HR), mean arterial pressure (MAP), recovery duration and quality.

Study Design: Prospective, masked, randomized clinical crossover trial.

Animals: A group of 40 client-owned dogs anaesthetized from October 2017 to June 2018.

Ethical dilemmas in clinical practice: a perspective on the results of an electronic survey of veterinary anaesthetists.

Medical progress has greatly advanced our ability to manage animals with critical and terminal diseases. We now have the ability to sustain life even in the most dire of circumstances. However, the preservation of life may not be synonymous with providing 'quality of life', and worse, could cause unnecessary suffering.

Systems analysis of voluntary reported anaesthetic safety incidents occurring in a university teaching hospital.

Objective: To identify factors contributing to the development of anaesthetic safety incidents.

Study Design: Prospective, descriptive, voluntary reporting audit of safety incidents with subsequent systems analysis.

Animals: All animals anaesthetized in a multispecies veterinary teaching hospital from November 2014 to October 2016.

CD133 glycosylation is enhanced by hypoxia in cultured glioma stem cells.

The cancer stem cell (CSC) marker CD133 is widely expressed in gliomas and employed mostly by use of the CD133/1 antibody which binds the extracellular glycosylated AC133 epitope. CD133 recognition may, however, be affected by its glycosylation pattern and oxygen tension. The present study investigates the effect of oxygen deprivation on CD133 expression and glycosylation status employing a high AC133-expressing glioblastoma multiforme (GBM) cell line, IN699.