Publications by authors named "Kristina Nedeljkovic"
The highly conserved oxytocin/vasopressin family of nonapeptides plays many roles across the animal kingdom, from osmoregulation to reproductive physiology. We investigated the expression patterns and pharmacological effects of the gastropod ortholog of this peptide, conopressin, along with another peptide involved in gastropod reproduction, APGWamide, in the nudibranch Berghia stephanieae. A brain transcriptome was used to identify and annotate the gene sequences for the peptides and one conopressin receptor.
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- The study analyzes the trends in prescribing gabapentinoids (gabapentin and pregabalin) to pediatric patients over a 7-year period, focusing on both labeled and off-label uses.
- Data was collected from a pediatric hospital, revealing that 93% of prescriptions were for gabapentin and that there was a notable increase in prescriptions during that time.
- Among patients referred to chronic pain clinics, many had stopped taking the medications due to side effects or lack of effectiveness, highlighting the diverse reasons for prescribing these drugs beyond their approved uses.