Publications by authors named "Kristina Dorzweiler"
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Synopsis of recent research by authors named "Kristina Dorzweiler"
Kristina Dorzweiler's research primarily focuses on the role of metalloproteases, particularly ADAM proteins, in cancer biology, investigating their functions in tumor progression, metastasis, and chemoresistance.
Her studies reveal that ADAM8 is significantly upregulated in pathological conditions such as inflammation and cancer, influencing processes like ectodomain shedding, which is critical for cell-cell communication in tumors.
She also emphasizes the importance of understanding metalloprotease activity profiles in body fluids like cerebrospinal fluid, which could serve as biomarkers for detecting neoplastic meningitis in cancer patients, highlighting their potential as therapeutic targets.
