Publications by authors named "Kristina Deak"
Oceans are major sinks for anthropogenic pollutants, including per- and polyfluoroalkyl substances (PFAS). Although PFAS have been detected in surface waters globally, this is the first report of PFAS in a deep (170-400 m) demersal species in the Gulf of Mexico (GoM). Golden Tilefish (Lopholatilus chamaeleonticeps) plasma extracts (n = 185) were investigated for the presence of PFAS using ultra-high performance liquid chromatography-tandem mass spectrometry.
View Article and Find Full Text PDFA review of the toxicology of oil in vertebrates: what we have learned following the oil spill.
J Toxicol Environ Health B Crit Rev
November 2021
Article Synopsis
- Following the DWH oil spill, extensive research was conducted by various organizations and institutions to understand the toxic effects of the oil on different species and humans.
- A workshop held eight years later highlighted the consistent toxic responses in various organisms, such as immune dysfunction and cardiotoxicity, indicating shared mechanisms of action across species.
- Observations indicated a progression of impacts from molecular and cellular changes to broader systemic effects, ultimately leading to critical health issues like multi-organ system failure in those exposed to high concentrations.
Background: The Deepwater Horizon (DWH) oil spill in 2010 released millions of barrels of crude oil into the northern Gulf of Mexico, exposing numerous species of animals to the toxic components of oil. A comprehensive assessment of morbidity and mortality caused by DWH oil exposure was undertaken by the DWH Natural Resource Damage Trustees to characterize ecosystem damages.
Objectives: This study aimed to characterize normal hematologic RIs in red drum fish with blood cell descriptions, and to demonstrate the importance of identifying and removing outliers when generating RI.
Congenital malformations are a prevalent cause of infant mortality in the United States and their induction has been linked to a variety of factors, including exposure to teratogens. However, the molecular mechanisms of teratogenicity are not fully understood. MicroRNAs are an important group of small, non-coding RNAs that regulate mRNA expression.
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