Publications by authors named "Kristina Blomberg"
Article Synopsis
- Transgenic expression of the laminin alpha1 chain prevents muscular dystrophy in mice lacking the laminin alpha2 chain.
- In these deficient mice, the synthesis of integrin alpha7Bbeta1D is increased, but the expression of the integrin alpha7B subunit at the muscle cell surface (sarcolemma) is reduced.
- Introducing laminin alpha1 chain restores the proper expression of integrin alpha7B and normalizes levels of alpha- and beta-dystroglycan, suggesting it helps maintain key binding sites that are crucial for muscle function.
