Publications by authors named "Kristina Barbara Helle"

Background: The recent outbreaks of Ebola virus disease (EVD) in Uganda and the Marburg virus disease (MVD) in Ghana reflect a persisting threat of Filoviridae to the global health community. Characteristic of Filoviridae are not just their high case fatality rates, but also that corpses are highly contagious and prone to cause infections in the absence of appropriate precautions. Vaccines against the most virulent Ebolavirus species, the Zaire ebolavirus (ZEBOV) are approved.

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Article Synopsis
  • - Governments worldwide adopted varying strategies to combat COVID-19, with some aiming for herd immunity despite the WHO deeming it unethical, leading to increased viral diversity and potential health risks.
  • - A study utilizing the CovidSim model investigated the impact of multi-infections on COVID-19 morbidity and mortality in the U.S., simulating scenarios of contact reductions and the spread of infections.
  • - Results showed that while multi-infections could lead to fewer overall infections due to higher isolation rates, they significantly increased mortality, highlighting the effectiveness of a potential second lockdown in reducing infections and deaths.
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Background: COVID-19 vaccines are approved, vaccination campaigns are launched, and worldwide return to normality seems within close reach. Nevertheless, concerns about the safety of COVID-19 vaccines arose, due to their fast emergency approval. In fact, the problem of antibody-dependent enhancement was raised in the context of COVID-19 vaccines.

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