Development and validation of the four-item Concise Aging adults Smell Test to screen for olfactory dysfunction in older adults.

Background: Olfactory dysfunction (OD) in the elderly is common and associated with numerous comorbidities, yet often underrecognized. This study sought to develop an instrument for widespread screening of this condition.

Methods: Demographic factors, comorbidities, and olfactory-related questions were examined in a focus group (N = 20) and development cohort (N = 190).

Intranasal Trigeminal Function in Aging Adults.

Background: Intranasal trigeminal function is important in detecting environmental stimuli. The impact of age-associated chemosensory dysfunction upon taste and olfaction is well described, but an understanding of trigeminal loss (chemesthesis) is lacking.

Objective: The goal of this study was to characterize trigeminal function in a cohort of older adults and explore potential impacts.

Treatment of sinus headache using a device that combines acoustic vibration with oscillating expiratory pressure.

Objective: To determine if simultaneous administration of acoustic vibration and oscillating expiratory pressure affects the severity of facial pain among patients with complaint of "sinus headache".

Methods: This is a prospective single-arm observational study performed at a tertiary care medical center. Subjects with complaint of sinus headache without evidence of chronic rhinosinusitis on exam or computed tomography participated in a clinical study applying simultaneous acoustic vibrations and positive expiratory pressure to the nasal cavity twice daily over 4 weeks.