Children integrate speech and gesture across a wider temporal window than speech and action when learning a math concept.

It is well established that gesture facilitates learning, but understanding the best way to harness gesture and how gesture helps learners are still open questions. Here, we consider one of the properties that may make gesture a powerful teaching tool: its temporal alignment with spoken language. Previous work shows that the simultaneity of speech and gesture matters when children receive instruction from a teacher (Congdon et al.

Serotonin and sudden death: differential effects of serotonergic drugs on seizure-induced respiratory arrest in DBA/1 mice.

In the DBA/1 mouse model of sudden unexpected death in epilepsy (SUDEP), administration of a selective serotonin (5-HT) reuptake inhibitor (SSRI), fluvoxamine, completely suppressed seizure-induced respiratory arrest (S-IRA) at 30 min after administration (i.p.) in a dose-related manner without blocking audiogenic seizures (AGSz), but another SSRI, paroxetine, reduced S-IRA but with a delayed (24 h) onset and significant toxicity.