Publications by authors named "Kristin M Favela"

Article Synopsis
  • Chronic high-fat diet in rodents leads to inflammation in the hypothalamus, which is linked to obesity and metabolic issues, but the impact of bariatric surgeries on this inflammation is unclear.* -
  • Two surgical procedures, Roux-en-Y gastric bypass and biliary diversion, were studied in mice, showing that both surgeries normalized inflammatory responses and microglial activity in the hypothalamus within 8 weeks, even while on a high-fat diet.* -
  • The results indicate that bariatric surgery not only alleviates inflammation but also restores the brain's sensitivity to leptin, highlighting its effectiveness in addressing obesity-related issues despite ongoing dietary challenges.*
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