Publications by authors named "Kristin L Fox"
Article Synopsis
- - The study aimed to review and meta-analyze RNA sequencing research comparing brain tissue from Alzheimer's disease patients to control subjects, focusing on study quality and identifying important genes and pathways linked to the disease.
- - Researchers examined 3,266 published studies and included 24 that met their criteria, discovering 571 differentially expressed genes in the temporal lobe and 189 in the frontal lobe, highlighting pathways like "Tube morphogenesis" and "Neuroactive ligand-receptor interaction."
- - The review faced challenges due to study differences and limited data but emphasizes that thorough methods are crucial for understanding Alzheimer's transcriptomic changes, which can help in the development of biomarkers and treatments.
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