Publications by authors named "Kristin Knauth"
Article Synopsis
- Current cancer immunotherapies primarily depend on CD8 T cells to kill tumor cells, but challenges arise from tumors with MHC deficiencies and immunosuppressive environments.*
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- New research highlights that even a small number of CD4 T cells can effectively target MHC-deficient tumors by clustering at tumor edges and interacting with specific antigen-presenting cells.*
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- The involvement of CD4 T cells leads to a shift in the immune response, enhancing the activation of tumor-killing myeloid cells and allowing for remote tumor destruction, suggesting a need for novel strategies that utilize CD4 T cells in cancer treatment.*
