Invasive Procedures Associated With Lung Cancer Screening in Clinical Practice.

Background: The harm associated with imaging abnormalities related to lung cancer screening (LCS) is not well documented, especially outside the clinical trial and academic setting.

Research Question: What is the frequency of invasive procedures and complications associated with a community based LCS program, including procedures for false-positive and benign, but clinically important, incidental findings?

Study Design And Methods: We performed a single-center retrospective study of an LCS program at a nonuniversity teaching hospital from 2016 through 2019 to identify invasive procedures prompted by LCS results, including their indication and complications.

Results: Among 2,003 LCS participants, 58 patients (2.