Publications by authors named "Kristin A Kinsman"
Background: The rapid adoption of electronic health records (EHRs) holds great promise for advancing medicine through practice-based knowledge discovery. However, the validity of EHR-based clinical research is questionable due to poor research reproducibility caused by the heterogeneity and complexity of healthcare institutions and EHR systems, the cross-disciplinary nature of the research team, and the lack of standard processes and best practices for conducting EHR-based clinical research.
Method: We developed a data abstraction framework to standardize the process for multi-site EHR-based clinical studies aiming to enhance research reproducibility.
Background: Silent brain infarction (SBI) is defined as the presence of 1 or more brain lesions, presumed to be because of vascular occlusion, found by neuroimaging (magnetic resonance imaging or computed tomography) in patients without clinical manifestations of stroke. It is more common than stroke and can be detected in 20% of healthy elderly people. Early detection of SBI may mitigate the risk of stroke by offering preventative treatment plans.
View Article and Find Full Text PDFPeripheral arterial disease (PAD) management is exceptionally challenging. Despite advances in diagnostic and therapeutic technologies, long-term vessel patency and limb salvage rates are limited. Patients with PAD frequently require extensive workup with noninvasive tests and imaging to delineate their disease and help guide appropriate management.
View Article and Find Full Text PDFArticle Synopsis
- The study aims to assess the safety and effectiveness of thermal ablation techniques for treating intrahepatic cholangiocarcinoma (ICC) and to identify factors leading to local tumor progression (LTP).
- A review of data from 20 patients who underwent treatment showed that RFA was the primary method used, with a high occurrence of metastases from prior surgical resections, and LTP developed in 22% of patients treated.
- The findings suggest that percutaneous thermal ablation is a safe option, particularly for patients with unresectable ICC, and that tumor size or treatment type did not significantly affect the recurrence rate, while the presence of primary tumors did.
Whole-Gland Prostate Cancer Cryoablation with Magnetic Resonance Imaging Guidance: One-Year Follow-Up.
Cardiovasc Intervent Radiol
February 2018
Purpose: Patients who develop prostate cancer after prior abdominal perineal resection are poor surgical candidates, and have limited treatment options. Therefore, our goal is to present results from a single institutional experience of four patients who underwent whole gland MRI-guided cryoablation with a history complicated by prior abdominoperineal resection.
Materials And Methods: Four MRI-guided cryoablative treatments (mean age 64, range 59-69 years) for primary and locally recurrent prostate adenocarcinoma were retrospectively reviewed in patients with prior abdominal perineal resection for colorectal cancer (3) and juvenile polyposis (1).