Publications by authors named "Kristiina Pold"

Article Synopsis
  • This study evaluates the clinical features and outcomes of acute cannabis toxicity versus acute synthetic cannabinoid receptor agonist toxicity in European emergency departments from 2013-2020.
  • Using data from the European Drug Emergencies Network Plus, researchers analyzed 2,657 cases of cannabis exposure and 503 cases of synthetic cannabinoid exposure to compare their effects.
  • The findings indicate that synthetic cannabinoid exposures are linked to more severe neuropsychiatric symptoms, while cannabis exposures are associated with cardiovascular issues.
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Article Synopsis
  • * Data from 11 centers across seven European countries revealed a wide variation in self-discharge rates, ranging from 1.7% to 17.1%, with synthetic cannabinoids and heroin use linked to higher rates of self-discharge.
  • * Strategies to enhance agitation management and the careful use of naloxone may help reduce self-discharge rates in ED settings.
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Objective: To analyse the relative percentage of acute recreational drug toxicity emergency department (ED) presentations involving the main drug groups according to age and sex and investigate different patterns based on sex and age strata.

Methods: We analysed all patients with acute recreational drug toxicity included by the Euro-DEN Plus dataset (22 EDs in 14 European countries) between October 2013 and December 2016 (39 months). Drugs were grouped as: opioids, cocaine, cannabis, amphetamines, gamma-hydroxybutyrate (GHB), hallucinogens, new psychoactive substances (NPS), benzodiazepines and ketamine.

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Objectives: To analyze epidemiologic, clinical, and care characteristics in cases in which patients came to 2 Spanish emergency departments (EDs) with symptoms caused by recreational drug abuse. To compare the characteristics with those reported for other areas of Europe.

Material And Methods: Secondary analysis of the registry of the European Drug Emergencies Network (Euro-DEN Plus), which collects cases in 14 European countries and 20 EDs.

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Article Synopsis
  • The study aimed to analyze the clinical profile of GHB (gamma-hydroxybutyrate) and GBL (gammabutyrolactone) intoxication among European patients, focusing on differences between those using these substances alone versus in combination with other drugs.
  • Data were collected over 12 months from Emergency Departments in the Euro-DEN network, including 710 intoxication cases, mostly affecting young males (mean age 31).
  • Key findings revealed that most patients arrived by ambulance during weekends, often combining GHB/GBL with other substances like alcohol and amphetamines, leading to a higher incidence of severe symptoms and longer hospital stays compared to those using GHB/GBL alone.
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