Publications by authors named "Kristie Walenczyk"
Objective: Among younger adults, to determine the associations of actigraph- and self-reported sleep duration with arterial stiffness (AS) assessed in clinic and in ecologically valid contexts, and to examine sex-specific associations.
Methods: Healthy adults ( n = 282, median age = 29 years, 67% women) completed a state-of-the-art assessment of AS at rest (SphygmoCor; carotid femoral pulse wave velocity [cfPWV]; central augmentation index [cAIx]) and 7 days of actigraphy-assessed sleep with concurrent, momentary cAIx assessment for 36 hours (Oscar-2). Multivariable regressions were conducted on the full sample and sex-stratified to examine cross-sectional linear and quadratic associations of average sleep duration with resting PWV and cAIx, average cAIx while awake and asleep, and nocturnal cAIx dipping, adjusted for demographic and health covariates.
Article Synopsis
- AJHP is publishing peer-reviewed manuscripts promptly online before final formatting, indicating that these versions are not the final published articles.
- The study investigates the diagnosis and treatment pathway of transthyretin cardiac amyloidosis (ATTR-CA), highlighting a significant gap between estimated prevalence and actual treatment rates among at-risk patients.
- Results showed that 58.8% of diagnosed patients were prescribed tafamidis, with 80.7% of those starting treatment, while factors like younger age, gender, and race influenced prescription and treatment initiation rates.
Article Synopsis
- The study explores the prevalence and impact of having both peripheral artery disease (PAD) and microvascular disease (MVD) in patients, using extensive data from hospital admissions across the U.S. between 2011 and 2018.
- Patients with both conditions faced increased risks of major and minor amputations, major cardiac events, and higher mortality rates compared to those with only PAD.
- The findings emphasize the need for more research focusing on this patient group due to their heightened vulnerability and health risks.
Background: Heart failure (HF) is common among people aging with HIV (PWH) and without HIV (PWoH). Despite the poor prognosis for HF, advance directives (AD) completion is low but has not been compared among PWH and PWoH.
Objectives: Determine the prevalence and predictors of AD screening among PWH and PWoH with incident HF.