Publications by authors named "Kristian Taekker Madsen"
Article Synopsis
- Coronary computed tomography angiography (CCTA) is useful for analyzing coronary atherosclerotic plaques, but previous studies on the consistency of plaque volume measurements between scans are limited.
- In a study involving 101 patients, CCTA scans were performed twice with a one-hour interval using identical protocols, and plaque volumes were assessed using semi-automated software.
- Results showed high correlation for total, non-calcified, and calcified plaques, but lower for low-density non-calcified plaques, with reproducibility influenced by image quality, reconstruction settings, and lesion location, particularly in left anterior descending (LAD) arteries.
Coronary CT angiography (CTA) derived fractional flow reserve (FFR) is recommended for physiological assessment in intermediate coronary stenosis for guiding referral to invasive coronary angiography (ICA). In this study, we report real-world data on the feasibility of implementing a CTA/FFR test algorithm as a gatekeeper to ICA at referral hospitals. Retrospective all-comer study of patients with new onset stable symptoms and suspected coronary stenosis (30-89%) by CTA.
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- A study examined the relationship between how completely patients with stable angina were revascularized (opened blocked arteries) and their cardiovascular health outcomes, using a method called fractional flow reserve (FFR) to measure artery health.
- In 900 patients, those who were incompletely revascularized had a significantly higher risk of cardiovascular events, like heart attacks, compared to those who were completely revascularized or had normal FFR readings.
- The findings suggest that ensuring complete revascularization in patients with critical artery blockages (FFR ≤ 0.80) could lead to better heart health outcomes.
Background: The association between coronary computed tomography angiography (CTA) derived fractional flow reserve (FFR) and risk of recurrent angina in patients with new onset stable angina pectoris (SAP) and stenosis by CTA is uncertain.
Methods: Multicenter 3-year follow-up study of patients presenting with symptoms suggestive of new onset SAP who underwent first-line CTA evaluation and subsequent standard-of-care treatment. All patients had at least one ≥30 % coronary stenosis.
Coronary CT angiography-derived fractional flow reserve in-stable angina: association with recurrent chest pain.
Eur Heart J Cardiovasc Imaging
October 2022
Aims: The aim of this study was to evaluate the association between coronary computed tomography angiography (CCTA)-derived fractional flow reserve (FFRCT) and recurrent chest pain (CP) at 1-year follow-up in patients with stable angina pectoris (SAP).
Methods And Results: Study of patients (n = 267) with SAP who underwent CCTA and FFRCT testing; 236 (88%) underwent invasive coronary angiography; and 87 (33%) were revascularized. Symptomatic status at 1-year follow-up was gathered by a structured interview.