Publications by authors named "Kristian T Madsen"
Article Synopsis
- Coronary computed tomography angiography (CCTA) is useful for analyzing coronary atherosclerotic plaques, but previous studies on the consistency of plaque volume measurements between scans are limited.
- In a study involving 101 patients, CCTA scans were performed twice with a one-hour interval using identical protocols, and plaque volumes were assessed using semi-automated software.
- Results showed high correlation for total, non-calcified, and calcified plaques, but lower for low-density non-calcified plaques, with reproducibility influenced by image quality, reconstruction settings, and lesion location, particularly in left anterior descending (LAD) arteries.
Coronary CT angiography (CTA) derived fractional flow reserve (FFR) is recommended for physiological assessment in intermediate coronary stenosis for guiding referral to invasive coronary angiography (ICA). In this study, we report real-world data on the feasibility of implementing a CTA/FFR test algorithm as a gatekeeper to ICA at referral hospitals. Retrospective all-comer study of patients with new onset stable symptoms and suspected coronary stenosis (30-89%) by CTA.
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- A study examined the relationship between how completely patients with stable angina were revascularized (opened blocked arteries) and their cardiovascular health outcomes, using a method called fractional flow reserve (FFR) to measure artery health.
- In 900 patients, those who were incompletely revascularized had a significantly higher risk of cardiovascular events, like heart attacks, compared to those who were completely revascularized or had normal FFR readings.
- The findings suggest that ensuring complete revascularization in patients with critical artery blockages (FFR ≤ 0.80) could lead to better heart health outcomes.
Background: The association between coronary computed tomography angiography (CTA) derived fractional flow reserve (FFR) and risk of recurrent angina in patients with new onset stable angina pectoris (SAP) and stenosis by CTA is uncertain.
Methods: Multicenter 3-year follow-up study of patients presenting with symptoms suggestive of new onset SAP who underwent first-line CTA evaluation and subsequent standard-of-care treatment. All patients had at least one ≥30 % coronary stenosis.
Background The prognostic value of coronary CT angiography (CTA)-derived fractional flow reserve (FFR) beyond 1-year outcomes and in patients with high levels of coronary artery calcium (CAC) is uncertain. Purpose To assess the prognostic value of coronary CTA-derived FFR test results on 3-year clinical outcomes in patients with coronary stenosis and among a subgroup of patients with high levels of CAC. Materials and Methods This study represents a 3-year follow-up of patients with new-onset stable angina pectoris who were consecutively enrolled in the Assessing Diagnostic Value of Noninvasive CT-FFR in Coronary Care, known as ADVANCE (ClinicalTrials.
View Article and Find Full Text PDFIntroduction: The enterococci are accountable for up to 20% of all cases of infective endocarditis, with being the primary causative isolate. Infective endocarditis is a life-threatening infection of the endocardium that results in the formation of vegetations. Based on a literature review, this paper provides an overview of the virulence factors associated with infective endocarditis.
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